# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3241055 | Physicochemical | Prodrug activation assessed as GSH reactivity in aqueous phosphate buffer at pH 7.4 by UV-Visible spectrophotometer analysis | 5 | ALA3232734 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3241056 | Physicochemical | Prodrug activation assessed as compound remaining in aqueous phosphate buffer at pH 7.4 measured after 2 half-lives by LC/MS analysis in presence of GSH | 1 | ALA3232734 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3241059 | Binding | Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins measured without activation by GSH by colorimetric analysis | Homo sapiens | 2 | ALA3232734 | single protein format | Scientific Literature | |
4. | ALA3241060 | Functional | In vitro antiproliferative activity against human NCI-H1568 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
5. | ALA3241061 | Functional | In vitro antiproliferative activity against human NCI-H1703 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
6. | ALA3241062 | Functional | In vitro antiproliferative activity against human H441 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
7. | ALA3241063 | Functional | In vitro antiproliferative activity against human NCI-H1693 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
8. | ALA3241064 | Functional | In vitro antiproliferative activity against human NCI-H2122 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
9. | ALA3241065 | Functional | In vitro antiproliferative activity against human NCI-H322M cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
10. | ALA3241066 | Functional | In vitro antiproliferative activity against human NCI-H1355 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
11. | ALA3241067 | Functional | In vitro antiproliferative activity against human H23 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
12. | ALA3241068 | Functional | In vitro antiproliferative activity against human NCI-H2030 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
13. | ALA3241069 | Functional | In vitro antiproliferative activity against human NCI-H1944 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
14. | ALA3241070 | Functional | In vitro antiproliferative activity against human NCI-H1792 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
15. | ALA3241071 | Functional | In vitro antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
16. | ALA3242900 | Functional | In vitro antiproliferative activity against human NCI-H2023 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
17. | ALA3242901 | Functional | In vitro antiproliferative activity against human H460 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay | Homo sapiens | 3 | ALA3232734 | cell-based format | Scientific Literature | |
18. | ALA3242902 | Functional | Increase in intracellular nitric oxide release in human NCI-H1703 cells at 10 uM after 30 mins by DAF-FM dye based luminescence spectrometer analysis | Homo sapiens | 2 | ALA3232734 | cell-based format | Scientific Literature | |
19. | ALA3242903 | Functional | Increase in intracellular reactive oxygen/nitrogen species in human NCI-H1703 cells at 10 uM after 60 mins by DCF-DA dye based luminescence spectrometer analysis | Homo sapiens | 2 | ALA3232734 | cell-based format | Scientific Literature | |
20. | ALA3242904 | Functional | Induction of DNA strand break damage in human NCI-H1703 cells at 5 uM after 24 hrs by comet assay | Homo sapiens | 1 | ALA3232734 | cell-based format | Scientific Literature |