# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3240083 | B | Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-AMC as substrate | Homo sapiens | 17 | ALA3232719 | protein complex format | Scientific Literature | |
2. | ALA3240084 | B | Inhibition of caspase-like activity of human 20S proteasome using Ac-nLPnLD-AMC as substrate | Homo sapiens | 13 | ALA3232719 | protein complex format | Scientific Literature | |
3. | ALA3240085 | B | Inhibition of trypsin-like activity of human 20S proteasome using Ac-RLR-AMC as substrate | Homo sapiens | 13 | ALA3232719 | protein complex format | Scientific Literature | |
4. | ALA3240086 | F | Inhibition of human HCT116 cell growth | Homo sapiens | 16 | ALA3232719 | cell-based format | Scientific Literature | |
5. | ALA3240088 | B | Inhibition of beta5 subunit of immunoproteasome (unknown origin) by active-site ELISA | Homo sapiens | 5 | ALA3232719 | single protein format | Scientific Literature | |
6. | ALA3240089 | B | Inhibition of beta5i subunit of immunoproteasome (unknown origin) by active-site ELISA | Homo sapiens | 5 | ALA3232719 | single protein format | Scientific Literature | |
7. | ALA3240090 | B | Inhibition of recombinant cathepsin A (unknown origin) using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH as substrate incubated with enzyme for 5 mins prior to substrate challenge for 2 hrs by spectrofluorometer analysis | Homo sapiens | 4 | ALA3232719 | single protein format | Scientific Literature | |
8. | ALA3240091 | B | Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC as substrate by spectrofluorometer analysis | Homo sapiens | 4 | ALA3232719 | single protein format | Scientific Literature | |
9. | ALA3240092 | B | Inhibition of recombinant cathepsin G (unknown origin) using Suc-Ala-Ala-Pro-Phe-AMC as substrate by spectrofluorometer analysis | Homo sapiens | 4 | ALA3232719 | single protein format | Scientific Literature | |
10. | ALA3240093 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G1 phase at 100 nM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 35.6%) | Homo sapiens | 3 | ALA3232719 | cell-based format | Scientific Literature | |
11. | ALA3240234 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at S phase at 100 nM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 45.3%) | Homo sapiens | 3 | ALA3232719 | cell-based format | Scientific Literature | |
12. | ALA3240235 | F | Cell cycle arrest in human HCT116 cells assessed as accumulation at G2/M phase at 100 nM after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 19.1%) | Homo sapiens | 3 | ALA3232719 | cell-based format | Scientific Literature | |
13. | ALA3240236 | F | Induction of apoptosis in human HCT116 cells assessed as increase in p53 expression by immunoblot analysis | Homo sapiens | 2 | ALA3232719 | cell-based format | Scientific Literature | |
14. | ALA3242186 | F | Induction of apoptosis in human HCT116 cells assessed as increase in PARP cleavage by immunoblot analysis | Homo sapiens | 2 | ALA3232719 | cell-based format | Scientific Literature | |
15. | ALA3242187 | B | Reversible inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-AMC as substrate measured after drug wash-out | Homo sapiens | 2 | ALA3232719 | protein complex format | Scientific Literature |