| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3240701 | Binding | Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by AlphaScreen assay | Homo sapiens | 40 | ALA3232863 | single protein format | Scientific Literature | |
| 2. | ALA3240702 | Binding | Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prior to glucose addition measured after 40 mins | Mus musculus | 39 | ALA3232863 | cell-based format | Scientific Literature | |
| 3. | ALA3240703 | ADME | Intrinsic clearance in rat liver microsomes after 30 mins in presence of NADPH | Rattus norvegicus | 40 | ALA3232863 | assay format | Scientific Literature | |
| 4. | ALA3240704 | ADME | Clearance in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 6 | ALA3232863 | organism-based format | Scientific Literature | |
| 5. | ALA3240705 | ADME | Half life in Sprague-Dawley rat at 2 mg/kg, iv | Rattus norvegicus | 6 | ALA3232863 | organism-based format | Scientific Literature | |
| 6. | ALA3240706 | ADME | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 7 | ALA3232863 | organism-based format | Scientific Literature | |
| 7. | ALA3240707 | ADME | AUC in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 6 | ALA3232863 | organism-based format | Scientific Literature |
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