# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3242464 | F | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum FcB1 infected in RBC assessed as inhibition of [3H]-hypoxanthine incorporation after 48 hrs by beta-counting | Plasmodium falciparum | 11 | ALA3232725 | organism-based format | Scientific Literature | |
2. | ALA3242465 | A | Cytotoxicity against human MCF7 cells after 48 hrs by XTT reduction assay | Homo sapiens | 11 | ALA3232725 | cell-based format | Scientific Literature | |
3. | ALA3242466 | F | Selectivity index, ratio of CC50 for human MCF7 cells to IC50 for chloroquine-resistant Plasmodium falciparum FcB1 infected in RBC | 11 | ALA3232725 | cell-based format | Scientific Literature | ||
4. | ALA4007866 | B | Inhibition of recombinant human IDO1 S167A mutant expressed in Escherichia coli SG13009(pREP4) using L-Tryptophan as substrate after 25 mins by fluorescence assay | Homo sapiens | 66 | ALA4007389 | assay format | Scientific Literature | |
5. | ALA4007878 | B | Inhibition of recombinant human IDO1 expressed in bacterial expression system at 350 uM using L-Tryptophan as substrate after 25 mins by fluorescence assay relative to control | Homo sapiens | 2 | ALA4007389 | assay format | Scientific Literature | |
6. | ALA4007890 | B | Inhibition of full length recombinant human His-tagged IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrs | Homo sapiens | 58 | ALA4007389 | cell-based format | Scientific Literature | |
7. | ALA4007891 | A | Cytotoxicity against mouse LLTC cells assessed as reduction in cell viability after 24 hrs by MTT assay | Mus musculus | 60 | ALA4007389 | cell-based format | Scientific Literature |