| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3257004 | B | Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysis | Sus scrofa | 53 | ALA3244260 | single protein format | Scientific Literature | |
| 2. | ALA4138637 | B | Inhibition of PRMT1 (unknown origin) assessed as residual enzyme activity by measuring methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 10 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 15 mins by scintillation proximity assay | Homo sapiens | 10 | ALA4138063 | single protein format | Scientific Literature | |
| 3. | ALA4138638 | B | Inhibition of PRMT1 (unknown origin) assessed as residual enzyme activity by measuring methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 100 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 15 mins by scintillation proximity assay | Homo sapiens | 10 | ALA4138063 | single protein format | Scientific Literature | |
| 4. | ALA4138640 | B | Inhibition of PRMT5 (unknown origin) assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 100 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 45 mins by scintillation proximity assay | Homo sapiens | 11 | ALA4138063 | single protein format | Scientific Literature | |
| 5. | ALA4138641 | B | Inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 10 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 15 mins by scintillation proximity assay | Homo sapiens | 5 | ALA4138063 | single protein format | Scientific Literature | |
| 6. | ALA4138642 | B | Inhibition of PRMT5 (unknown origin) assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin pre-incubated for 3 mins before [3H]-SAM addition and measured after 45 mins by scintillation proximity assay | Homo sapiens | 5 | ALA4138063 | single protein format | Scientific Literature | |
| 7. | ALA4138643 | B | Potency index, ratio of IC50 for furamidine to IC50 for test compouhnd for inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 10 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 15 mins by scintillation proximity assay | Homo sapiens | 1 | ALA4138063 | single protein format | Scientific Literature | |
| 8. | ALA4138644 | B | Potency index, ratio of IC50 for stilbamidine to IC50 for test compouhnd for inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H4-20-Biotin at 10 uM pre-incubated for 3 mins before [3H]-SAM addition and measured after 15 mins by scintillation proximity assay | Homo sapiens | 1 | ALA4138063 | single protein format | Scientific Literature | |
| 9. | ALA4138645 | B | Inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from SAM to biotinylated histone H4 peptide H4-20-Biotin at 0.2 mM incubated for 3.5 hrs by mass spectrometry | Homo sapiens | 2 | ALA4138063 | single protein format | Scientific Literature | |
| 10. | ALA4138646 | B | Inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from SAM to biotinylated histone H4 peptide H4-20-Biotin at 0.5 mM incubated for 3.5 hrs by mass spectrometry | Homo sapiens | 1 | ALA4138063 | single protein format | Scientific Literature | |
| 11. | ALA4138647 | B | Inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from [14C]SAM to biotinylated histone H4 peptide H4-20-Biotin at 0.2 mM incubated for 30 mins by radiometric gel assay | Homo sapiens | 2 | ALA4138063 | single protein format | Scientific Literature | |
| 12. | ALA4138648 | B | Inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from [14C]SAM to biotinylated histone H4 peptide H4-20-Biotin at 0.1 mM incubated for 30 mins by radiometric gel assay | Homo sapiens | 2 | ALA4138063 | single protein format | Scientific Literature | |
| 13. | ALA4138649 | B | Inhibition of PRMT1 (unknown origin) assessed as reduction in methyl transfer from [14C]SAM to biotinylated histone H4 peptide H4-20-Biotin at 0.05 mM incubated for 30 mins by radiometric gel assay | Homo sapiens | 1 | ALA4138063 | single protein format | Scientific Literature | |
| 14. | ALA5138230 | B | Inhibition of PRMT1 (unknown origin) | Homo sapiens | 10 | ALA5136992 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!