# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3258878 | F | Neuroleptic activity in ip dosed mouse assessed as inhibition of amphetamine-induced mortality | Mus musculus | 11 | organism-based format | Scientific Literature | ||
2. | ALA3258879 | F | Neuroleptic activity in ip dosed rat assessed as drug required for blocking discriminated jump-out avoidance behavior in after 1 hr | Rattus norvegicus | 14 | organism-based format | Scientific Literature | ||
3. | ALA3258880 | F | Analgesic activity in rat assessed as median foot shock required to elicit flinch-jump at 32 mg/kg, ip after 2 hrs | Rattus norvegicus | 54 | organism-based format | Scientific Literature | ||
4. | ALA3258883 | F | Analgesic activity in dog assessed as rippling of skin at 10 mg/kg, po after 2 hrs by radiant heat assay | Canis lupus familiaris | 8 | organism-based format | Scientific Literature | ||
5. | ALA3258887 | F | Analgesic activity in mouse at 100 mg/kg, ip after 2 hrs by hot plate assay | Mus musculus | 51 | organism-based format | Scientific Literature | ||
6. | ALA3258890 | F | Analgesic activity in mouse assessed as tail-flick latency period at 100 mg/kg, ip after 2 hrs by by tail flick test | Mus musculus | 51 | organism-based format | Scientific Literature | ||
7. | ALA3382363 | B | Inhibition of C-terminal poly-His-tagged Escherichia coli MetAP expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition by fluorescence assay | Escherichia coli | 32 | assay format | Scientific Literature | ||
8. | ALA3382364 | B | Inhibition of N-terminal poly-His-tagged Staphylococcus aureus COL MetAP expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition by fluorescence assay | Staphylococcus aureus subsp. aureus COL | 32 | assay format | Scientific Literature | ||
9. | ALA3384241 | B | Inhibition of N-terminal poly-His-tagged human MetAP-1 expressed in Escherichia coli BL21(DE3) incubated for 30 mins before MGMM substrate addition by fluorescence assay | Homo sapiens | 32 | assay format | Scientific Literature | ||
10. | ALA3384242 | B | Inhibition of human MetAP-2 expressed in Sf9 cells incubated for 60 mins before MGMM substrate addition by fluorescence assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
11. | ALA3384243 | F | Antimicrobial activity against Escherichia coli BL21(DE3) assessed as inhibition of bacterial growth at 200 uM incubated at 37 degC for 7 hrs | Escherichia coli | 32 | assay format | Scientific Literature | ||
12. | ALA3384245 | P | Half life assessed as decomposition into amines and unsaturated ketones at 250 uM in 50 mM Tris/maleate pH 7.5 buffer by HPLC method | 25 | small-molecule physicochemical format | Scientific Literature | |||
13. | ALA3384247 | A | Cytotoxicity against human HaCaT cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
14. | ALA3384248 | A | Cytotoxicity against human Flow 2002 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
15. | ALA3384249 | F | Cytotoxicity against human A172 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
16. | ALA3384250 | F | Cytotoxicity against human Capan1 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
17. | ALA3384251 | F | Cytotoxicity against human CaSki cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
18. | ALA3384252 | F | Cytotoxicity against human SW707 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
19. | ALA3384253 | F | Cytotoxicity against human Calu6 cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
20. | ALA3384254 | F | Cytotoxicity against human MeWo cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | cell-based format | Scientific Literature |