| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3252441 | F | Antimalarial activity against Plasmodium berghei KBG 173 infected in ICR/HA Swiss mouse assessed as increase in mean survival time at 40 mg/kg, sc administered 72 hrs post infection | Plasmodium berghei | 82 | organism-based format | Scientific Literature | ||
| 2. | ALA3252443 | F | Antimalarial activity against Plasmodium berghei KBG 173 infected in ICR/HA Swiss mouse assessed as increase in mean survival time at 160 mg/kg, sc administered 72 hrs post infection | Plasmodium berghei | 82 | organism-based format | Scientific Literature | ||
| 3. | ALA3252445 | F | Antimalarial activity against Plasmodium berghei KBG 173 infected in ICR/HA Swiss mouse assessed as increase in mean survival time at 640 mg/kg, sc administered 72 hrs post infection | Plasmodium berghei | 68 | organism-based format | Scientific Literature | ||
| 4. | ALA4687162 | F | Induction of cell cycle arrest in human MGC-803 cells assessed as accumulation at G0/G1 phase at 12 nM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 68.72 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4687163 | F | Antiproliferative activity against human MGC-803 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 6. | ALA4687164 | A | Cytotoxicity against human GES1 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA4687165 | U | Selectivity index, ratio of IC50 for cytotoxicity against human GES1 to IC50 for antiproliferative activity against human MGC-803 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 8. | ALA4687166 | F | Antiproliferative activity against human HGC-27 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4687167 | F | Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 10. | ALA4687168 | F | Antiproliferative activity against human BGC-823 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4687169 | F | Antiproliferative activity against human EC9706 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4687170 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA4687171 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA4687172 | F | Inhibition of colony formation in human MGC-803 cells assessed as reduction in colony number at 4 to 12 nM incubated for 10 days by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4687173 | F | Inhibition of colony formation in human MGC-803 cells assessed as reduction in colony size at 4 to 12 nM incubated for 10 days by crystal violet staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4687174 | F | Induction of cell cycle arrest in human MGC-803 cells assessed as accumulation at G0/G1 phase at 4 nM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 68.72 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4687175 | F | Induction of cell cycle arrest in human MGC-803 cells assessed as accumulation at S phase at 4 nM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 12.76 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4687176 | F | Induction of cell cycle arrest in human MGC-803 cells assessed as accumulation at G2/M phase at 4 nM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 15.54 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4687177 | F | Induction of cell cycle arrest in human MGC-803 cells assessed as accumulation at G0/G1 phase at 8 nM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 68.72 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4687178 | F | Induction of cell cycle arrest in human MGC-803 cells assessed as accumulation at S phase at 8 nM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 12.76 %) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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