# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3255390 | T | Toxicity in ferret infected with Influenza A virus Port Chalmers/1/73 (H3N2) assessed as change in body weight at 13 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured after 7 days relative to untreated control | Mustela putorius furo | 2 | organism-based format | Scientific Literature | ||
2. | ALA3255391 | T | Toxicity in ferret infected with Influenza A virus Port Chalmers/1/73 (H3N2) assessed as change in body weight at 8 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured after 7 days relative to untreated control | Mustela putorius furo | 1 | organism-based format | Scientific Literature | ||
3. | ALA3255392 | T | Toxicity in ferret infected with Influenza A virus Port Chalmers/1/73 (H3N2) assessed as change in body weight at 16 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured after 7 days relative to untreated control | Mustela putorius furo | 1 | organism-based format | Scientific Literature | ||
4. | ALA3255393 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in rectal temperature at 8 to 16 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
5. | ALA3255398 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 13 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 2 measured on day 2 relative to untreated control | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
6. | ALA3255399 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 13 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured on day 3 relative to untreated control | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
7. | ALA3255400 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 13 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured on day 4 relative to untreated control | Influenza A virus | 2 | organism-based format | Scientific Literature | ||
8. | ALA3255404 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 8 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 2 measured on day 2 relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
9. | ALA3255405 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 8 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured on day 3 relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
10. | ALA3255809 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 8 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured on day 4 relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
11. | ALA3255810 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 16 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 2 measured on day 2 relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
12. | ALA3255811 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 16 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured on day 3 relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
13. | ALA3255812 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as reduction in viral excretion by measuring hemagglutination units per ml at 16 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 measured on day 4 relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
14. | ALA3255813 | F | Antiviral activity against Influenza A virus Port Chalmers/1/73 (H3N2) infected in ferret assessed as serum antibody response to virus infection at 16 mg/kg administered intranasally 7 times on day 0 and 9 times on day 1 to day 3 by serum antibody response test relative to untreated control | Influenza A virus | 1 | organism-based format | Scientific Literature | ||
15. | ALA3257215 | P | Solubility in water | 7 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA3257217 | P | Stability in unbuffered aqueous solutions at pH >6 assessed as compound hydrolysis | 4 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA3257218 | P | Stability in unbuffered aqueous solutions at pH >6 assessed as compound decarboxylation | 4 | small-molecule physicochemical format | Scientific Literature |