# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3253106 | B | Inhibition of noradrenaline transporter in NMRI albino mouse brain assessed as [3H]NA accumulation in hypothalamus after 5 mins | Mus musculus | 6 | ALA3244106 | tissue-based format | Scientific Literature | |
2. | ALA3253107 | B | Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 mins | Mus musculus | 6 | ALA3244106 | tissue-based format | Scientific Literature | |
3. | ALA3253108 | F | Antidepressant activity in ip dosed NMRI albino mouse assessed as inhibition of [3H]NA accumulation in hypothalamus after 0.5 hrs | Mus musculus | 6 | ALA3244106 | organism-based format | Scientific Literature | |
4. | ALA3253109 | F | Antidepressant activity in ip dosed NMRI albino mouse assessed as inhibition of [3H]5-HT accumulation in hypothalamus after 0.5 hrs | Mus musculus | 6 | ALA3244106 | organism-based format | Scientific Literature | |
5. | ALA3253110 | F | Antidepressant activity in ip dosed NMRI albino mouse assessed as inhibition of [3H]DA accumulation in hypothalamus after 0.5 hrs | Mus musculus | 6 | ALA3244106 | organism-based format | Scientific Literature | |
6. | ALA3253111 | F | Potentiation of 5-HTP-induced head twitches in ip dosed NMRI albino mouse administered 1 hr prior to 5-HTP challenge | Mus musculus | 6 | ALA3244106 | organism-based format | Scientific Literature | |
7. | ALA3253112 | F | Mydriatic effect in iv dosed NMRI albino mouse assessed as concentration required to increase pupil diameter by 200% | Mus musculus | 5 | ALA3244106 | organism-based format | Scientific Literature | |
8. | ALA3253113 | T | Acute toxicity in iv dosed NMRI albino mouse assessed as lethality up to 24 hrs | Mus musculus | 5 | ALA3244106 | organism-based format | Scientific Literature | |
9. | ALA3253114 | F | Antidepressant activity in NMRI albino mouse assessed as increase in locomotion at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature | |
10. | ALA3253115 | F | Antidepressant activity in NMRI albino mouse assessed as hyperactivity by measuring motor excitation at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature | |
11. | ALA3253116 | F | Antidepressant activity in NMRI albino mouse assessed as hyperactivity by measuring irritability at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature | |
12. | ALA3253117 | F | Antidepressant activity in NMRI albino mouse assessed as hyperactivity by measuring sniffing at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature | |
13. | ALA3253118 | F | Antidepressant activity in NMRI albino mouse assessed as hyperactivity by measuring tremor at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature | |
14. | ALA3253556 | F | Antidepressant activity in NMRI albino mouse assessed as hyperactivity by measuring rearing at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature | |
15. | ALA3253557 | F | Antidepressant activity in NMRI albino mouse assessed as hyperactivity by measuring circling of head at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature | |
16. | ALA3253558 | F | Antidepressant activity in NMRI albino mouse assessed as hyperactivity by measuring repetitive movements of head at 20 mg/kg, ip after 2 hrs relative to vehicle-treated control | Mus musculus | 3 | ALA3244106 | organism-based format | Scientific Literature |