#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3271333	Binding	Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based analysis	Homo sapiens	29	ALA3259558	cell-based format	Scientific Literature
2.	ALA3271334	Functional	Antiproliferative activity against human A2780 cells assessed as cell viability after 72 hrs by SRB assay	Homo sapiens	28	ALA3259558	cell-based format	Scientific Literature
3.	ALA3271335	ADME	Apparent permeability from apical to basolateral side in MDCK cells at 10 uM by LC-MS/MS analysis	Canis lupus familiaris	9	ALA3259558	cell-based format	Scientific Literature
4.	ALA3271336	ADME	Fraction unbound in mouse plasma at 5 uM by LC-MS/MS analysis	Mus musculus	10	ALA3259558	cell-free format	Scientific Literature
5.	ALA3271337	Physicochemical	Aqueous solubility of the compound in PBS at pH 7.2 by LC/CLND analysis		9	ALA3259558	small-molecule physicochemical format	Scientific Literature
6.	ALA3271338	ADME	Cmax in NCR nude mouse at 100 mg/kg, po	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
7.	ALA3271339	ADME	Tmax in NCR nude mouse at 100 mg/kg, po	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
8.	ALA3271340	ADME	Volume of distribution at steady state in NCR nude mouse at 5 mg/kg, iv	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
9.	ALA3271341	ADME	Clearance in NCR nude mouse at 5 mg/kg, iv	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
10.	ALA3271342	ADME	Half life in NCR nude mouse at 5 mg/kg, iv	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
11.	ALA3271343	ADME	Half life in NCR nude mouse at 100 mg/kg, po	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
12.	ALA3271344	Functional	Antitumor activity against human A2780 cells xenografted in NCR nude mouse assessed as tumor regression at 100 mg/kg, po qd measured for 5 to 15 days	Homo sapiens	1	ALA3259558	organism-based format	Scientific Literature
13.	ALA3271345	Toxicity	Toxicity in NCR nude mouse xenografted with human A2780 cells assessed as decrease in body weight at 100 mg/kg, po qd measured after 5 days	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
14.	ALA3271346	Functional	Reduction of NAD level in tumor of NCR nude mouse xenografted with human A2780 cells at 100 mg/kg, po qd measured after day-5 dose for 1 to 24 hrs relative to vehicle-treated control	Mus musculus	1	ALA3259558	organism-based format	Scientific Literature
15.	ALA3271349	ADME	Drug uptake in Sprague-Dawley rat retina at 30 mg/kg, po qd for 2 days measured 1 hr after last dose	Rattus norvegicus	1	ALA3259558	organism-based format	Scientific Literature
16.	ALA3271350	ADME	Drug uptake in Sprague-Dawley rat retina at 30 mg/kg, po qd for 2 days measured 6.5 hrs after last dose	Rattus norvegicus	1	ALA3259558	organism-based format	Scientific Literature
17.	ALA3271353	ADME	Ratio of drug level in retina to plasma of Sprague-Dawley rat at 30 mg/kg, po qd for 2 days measured 1 hr after last dose	Rattus norvegicus	1	ALA3259558	organism-based format	Scientific Literature
18.	ALA3271354	ADME	Ratio of drug level in retina to plasma of Sprague-Dawley rat at 30 mg/kg, po qd for 2 days measured 6.5 hrs after last dose	Rattus norvegicus	1	ALA3259558	organism-based format	Scientific Literature
19.	ALA3271355	Binding	Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysis	Mus musculus	2	ALA3259558	single protein format	Scientific Literature
20.	ALA3271356	Binding	Inhibition of rat NAMPT after 30 mins by mass spectrometry-based analysis	Rattus norvegicus	2	ALA3259558	single protein format	Scientific Literature