| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3267301 | B | Agonist activity at lipoprotein lipase (unknown origin) using p-nitrophenylbutyrate as substrate by spectrophotometric analysis relative to control | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 2. | ALA3267302 | B | Activation of lipoprotein lipase (unknown origin) assessed as reversal of ANGPTL4-mediated enzyme inhibition treated with ANGPTL4 for 30 mins followed by substrate addition measured after 20 mins by spectrophotometric analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA3267303 | B | Agonist activity at lipoprotein lipase (unknown origin) using p-nitrophenylbutyrate as substrate by spectrophotometric analysis relative to NO-1886 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3863230 | B | Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichia coli BL21 by scintillation proximity assay | Homo sapiens | 86 | assay format | Scientific Literature | ||
| 5. | ALA3863231 | B | Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichia coli BL21 by Cheng-Prusoff analysis | Homo sapiens | 86 | assay format | Scientific Literature | ||
| 6. | ALA3874159 | F | In vivo activation of lipoprotein lipase in high fat diet fed C57BL/6 mouse assessed as reduction in total body fat content at 1 to 10 mg/kg, ip administered daily on last week of 4 months study until end | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3874160 | B | Binding affinity to bovine recombinant lipoprotein lipase assessed as Km for substrate using p-Nitrophenyl butyrate as substrate by Lineweaver-Burk plot analysis (Rvb = 8.15 mM) | Bos taurus | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3874161 | B | Activation of bovine recombinant lipoprotein lipase at 100 uM using p-Nitrophenyl butyrate as substrate by HTS assay | Bos taurus | 5 | single protein format | Scientific Literature | ||
| 9. | ALA3874163 | F | In vivo activation of lipoprotein lipase in high fat diet fed C57BL/6 mouse at 10 mg/kg, ip administered daily on last week of 4 months study until end by fluorescence assay | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA3874164 | F | In vivo activation of lipoprotein lipase in high fat diet fed C57BL/6 mouse at 1 to 5 mg/kg, ip administered daily on last week of 4 months study until end by fluorescence assay | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3874165 | F | Reduction in serum cholesterol level in high fat diet fed C57BL/6 mouse at 10 mg/kg, ip administered daily on last week of 4 months study until end | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3874166 | F | In vivo activation of lipoprotein lipase in high fat diet fed C57BL/6 mouse assessed as reduction in body weight at 1 to 10 mg/kg, ip administered daily on last week of 4 months study until end | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3874167 | F | Reduction in lipid accumulation in high fat diet fed C57BL/6 mouse liver at 10 mg/kg, ip administered daily on last week of 4 months study until end by hematoxylin and eosin staining based assay | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3874168 | F | Reduction in serum triglycerides level in high fat diet fed C57BL/6 mouse at 10 mg/kg, ip administered daily on last week of 4 months study until end | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA3874169 | F | Hepatoprotective activity against high fat diet fed C57BL/6 mouse liver assessed as increase in SIRT1 level at 10 mg/kg, ip administered daily on last week of 4 months study until end | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA3874170 | F | Hepatoprotective activity against high fat diet fed C57BL/6 mouse liver assessed as increase in LC3 level at 10 mg/kg, ip administered daily on last week of 4 months study until end | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3874171 | B | Activation of bovine recombinant lipoprotein lipase at 100 uM using p-Nitrophenyl butyrate as substrate by HTS assay relative to NO-1886 | Bos taurus | 1 | single protein format | Scientific Literature | ||
| 18. | ALA3874172 | T | Toxicity in high fat diet fed C57BL/6 mouse liver assessed as morphological changes at 10 mg/kg, ip administered daily on last week of 4 months study until end by hematoxylin and eosin staining based assay | Mus musculus | 1 | organism-based format | Scientific Literature |
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