| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3270056 | B | Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by Fluo-4/AM assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 2. | ALA3270057 | B | Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction | Rattus norvegicus | 24 | tissue-based format | Scientific Literature | ||
| 3. | ALA3270059 | F | Neuroprotective activity against K+ induced Ca2+ overload in human SH-SY5Y cells assessed as survival at 5 uM after 24 hrs by MTT assay (Rvb = 52.1 +/- 3.5%) | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 4. | ALA3265719 | F | Neuroprotective activity against K+ induced Ca2+ overload in human SH-SY5Y cells assessed as protection at 5 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 5. | ALA3265720 | F | Neuroprotective activity against rotenone-oligomycin A-induced oxidative stress in human SH-SY5Y cells assessed as survival at 5 uM co-incubated rot/oligo for 24 hrs by MTT assay (Rvb =65.6 +/- 1.3%) | Homo sapiens | 24 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!