| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3269774 | B | Agonist activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assay | Homo sapiens | 47 | ALA3259572 | cell-based format | Scientific Literature | |
| 2. | ALA3269775 | B | Agonist activity at human recombinant TLR2/6 expressed in HEK293 cells at 10 uM by SEAP reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 3. | ALA3269776 | A | Cytotoxicity against human PBMC by WST-1 cell proliferation assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 4. | ALA3269777 | A | Cytotoxicity against PHA-stimulated human PBMC at 20 uM by WST-1 cell proliferation assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 5. | ALA3270131 | B | Agonist activity at chimeric extracellular domain of human TLR4 fused with human intracellular domain expressed in HEK293 cells by NFkappaB reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 6. | ALA3270132 | B | Agonist activity at chimeric extracellular domain of human TLR4 fused with mouse intracellular domain expressed in HEK293 cells by NFkappaB reporter assay | 1 | ALA3259572 | cell-based format | Scientific Literature | ||
| 7. | ALA3270133 | B | Agonist activity at human recombinant TLR3 expressed in HEK293 cells at 10 uM by SEAP reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 8. | ALA3270134 | B | Agonist activity at human recombinant TLR5 expressed in HEK293 cells at 10 uM by SEAP reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 9. | ALA3270135 | B | Agonist activity at human recombinant TLR7 expressed in HEK293 cells at 10 uM by SEAP reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 10. | ALA3270136 | B | Agonist activity at human recombinant TLR8 expressed in HEK293 cells at 10 uM by SEAP reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 11. | ALA3270137 | B | Agonist activity at human recombinant TLR4 expressed in HEK293 cells coexpressed with human MD2 assessed as TNFalpha response by NFkappaB reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 12. | ALA3270138 | B | Agonist activity at human recombinant TLR4 expressed in HEK293 cells coexpressed with mouse MD2 assessed as TNFalpha response by NFkappaB reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 13. | ALA3270139 | F | Induction of IL-12p40 production in human PBMC at 10 uM by ELISA | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 14. | ALA3270140 | F | Induction of IL-10 production in human PBMC at 10 uM by ELISA | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 15. | ALA3270141 | F | Induction of TNFalpha production in human PBMC at 10 uM by ELISA | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 16. | ALA3270142 | F | Induction of IL-8 production in human PBMC at 10 uM by ELISA | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 17. | ALA3270143 | F | Suppression of PHA-induced IL-5 release in human PBMC at 10 uM by ELISA | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 18. | ALA3270150 | B | Intrinsic activity at human recombinant TLR4 expressed in HEK293 cells by SEAP reporter assay relative to LPS | Homo sapiens | 39 | ALA3259572 | cell-based format | Scientific Literature | |
| 19. | ALA3270151 | B | Agonist activity at human recombinant TLR2 expressed in HEK293 cells by SEAP reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature | |
| 20. | ALA3270152 | B | Agonist activity at human recombinant TLR9 expressed in HEK293 cells at 10 uM by SEAP reporter assay | Homo sapiens | 1 | ALA3259572 | cell-based format | Scientific Literature |
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