# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3384820 | Binding | Inhibition of Leptosphaeria sacchari tyrosinase using L-DOPA as substrate incubated for 10 mins prior to substrate addition measured after 10 mins by spectrophotometry | Leptosphaeria sacchari | 13 | ALA3351826 | assay format | Scientific Literature | |
2. | ALA3384821 | Binding | Inhibition of Leptosphaeria sacchari tyrosinase using L-DOPA as substrate at 0.3 mg/ml incubated for 10 mins prior to substrate addition measured after 10 mins by spectrophotometry | Leptosphaeria sacchari | 13 | ALA3351826 | assay format | Scientific Literature | |
3. | ALA3384822 | Binding | Inhibition of Leptosphaeria sacchari tyrosinase using L-DOPA as substrate assessed as remaining activity at 0.3 mg/ml incubated for 10 mins prior to substrate addition measured after 10 mins by spectrophotometry | Leptosphaeria sacchari | 13 | ALA3351826 | assay format | Scientific Literature | |
4. | ALA3384825 | Binding | Inhibition of rabbit platelet PDE5A using [3H]cGMP as substrate at 1 uM after 30 mins by scintillation proximity assay | Oryctolagus cuniculus | 15 | ALA3351826 | assay format | Scientific Literature | |
5. | ALA3270126 | Functional | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay | Homo sapiens | 19 | ALA3259714 | cell-based format | Scientific Literature | |
6. | ALA3270127 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 24 hrs by MTT assay | Homo sapiens | 19 | ALA3259714 | cell-based format | Scientific Literature | |
7. | ALA3270128 | Functional | Cytostatic activity against human MCF7 cells assessed as inhibition of DNA synthesis after 24 hrs by [3H]thymidine incorporation assay | Homo sapiens | 19 | ALA3259714 | cell-based format | Scientific Literature | |
8. | ALA3270129 | Functional | Cytostatic activity against human MDA-MB-231 cells assessed as inhibition of DNA synthesis after 24 hrs by [3H]thymidine incorporation assay | Homo sapiens | 19 | ALA3259714 | cell-based format | Scientific Literature | |
9. | ALA3407084 | Functional | Cytotoxicity against human MCF7 cells after 72 hrs using Calcein AM by fluorescence assay | Homo sapiens | 17 | ALA3400118 | cell-based format | Scientific Literature | |
10. | ALA3407085 | Functional | Cytotoxicity against human K562 cells after 72 hrs using Calcein AM by fluorescence assay | Homo sapiens | 17 | ALA3400118 | cell-based format | Scientific Literature | |
11. | ALA3407086 | Binding | Inhibition of CDK2/Cyclin E (unknown origin) using histone H1 as substrate by [gamma-33P]ATP assay | Homo sapiens | 17 | ALA3400118 | protein complex format | Scientific Literature | |
12. | ALA3407087 | Binding | Inhibition of Abl (unknown origin) using GGEAIYAAPFKK peptide as substrate by [gamma-33P]ATP assay | Homo sapiens | 17 | ALA3400118 | single protein format | Scientific Literature | |
13. | ALA3407088 | Binding | Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration assay | Homo sapiens | 16 | ALA3400118 | single protein format | Scientific Literature | |
14. | ALA3407089 | Binding | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration assay | Homo sapiens | 16 | ALA3400118 | single protein format | Scientific Literature | |
15. | ALA3407090 | Binding | Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration assay | Homo sapiens | 16 | ALA3400118 | single protein format | Scientific Literature | |
16. | ALA3407091 | Binding | Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration assay | Homo sapiens | 16 | ALA3400118 | single protein format | Scientific Literature | |
17. | ALA5242035 | Binding | Inhibition of tyrosinase (unknown origin) relative to control | Homo sapiens | 1 | ALA5241085 | single protein format | Scientific Literature | |
18. | ALA5242036 | Binding | Inhibition of tyrosinase (unknown origin) assessed as enzyme residual activity at 0.07 mg/ml relative to control | Homo sapiens | 1 | ALA5241085 | single protein format | Scientific Literature |