| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3266696 | B | Inhibition of recombinant human cathepsin C using H-Gly-Arg-AMC as substrate preincubated for 30 mins before substrate addition measured after 60 mins by fluorescence assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 2. | ALA3266697 | B | Inhibition of cathepsin C in human THP1 cells assessed as inhibition of H-Gly-Phe-AFC cleavage by fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 3. | ALA3266698 | A | Intrinsic clearance in human microsomes | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 4. | ALA3266699 | A | Intrinsic clearance in rat hepatocytes assessed per million cells | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA3266700 | B | Inhibition of human ERG by electrophysiology assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 6. | ALA3266710 | A | Clearance in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA3266711 | A | Volume of distribution at steady state in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA3266712 | A | Half life in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA3266713 | A | Bioavailability in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA3266714 | P | Lipophilicity, log D of the compound | 9 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA3268202 | P | Dissociation constant, pKa of the compound | 8 | small-molecule physicochemical format | Scientific Literature | |||
| 12. | ALA3268203 | B | Inhibition of Cathepsin K (unknown origin) | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 13. | ALA3268204 | B | Inhibition of Cathepsin L (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 14. | ALA3268205 | B | Inhibition of Cathepsin S (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 15. | ALA3268206 | B | Inhibition of Cathepsin B (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 16. | ALA3268207 | A | Induction of phospholipid accumulation in rat hepatoma cells | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA3268208 | T | Toxicity in rat assessed as liver hypertrophy | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA3268209 | T | Toxicity in rat assessed as liver cholangitis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA3268210 | T | Toxicity in rat assessed as liver vacuolation | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA3268211 | T | Toxicity in rat assessed as foci of foaming macrophages in lung | Rattus norvegicus | 2 | organism-based format | Scientific Literature |
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