# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3267120 | P | Dissociation constant, pKa of the compound in buffered solution containing 5% DMSO at 100 uM by absorbance analysis | 37 | ALA3259557 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3267121 | P | Retention time of the compound by HPLC analysis | 40 | ALA3259557 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA3267122 | B | Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's method | Homo sapiens | 31 | ALA3259557 | single protein format | Scientific Literature | |
4. | ALA3267123 | B | Inhibition of recombinant N-terminal His6-tagged mouse NAT2 expressed in Escherichia coli Rosetta(DE3)pLysS cells assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's method | Mus musculus | 31 | ALA3259557 | cell-based format | Scientific Literature | |
5. | ALA3267125 | B | Inhibition of NAT1 in human ZR-75-1 cells assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate at 1 uM by Ellman's method | Homo sapiens | 4 | ALA3259557 | cell-based format | Scientific Literature | |
6. | ALA3267126 | B | Inhibition of N-terminal His6-tagged mouse NAT2 R127G mutant expressed in Escherichia coli Rosetta(DE3)pLysS cells | Mus musculus | 1 | ALA3259557 | cell-based format | Scientific Literature | |
7. | ALA3267127 | B | Inhibition of N-terminal His6-tagged mouse NAT2 R127L mutant expressed in Escherichia coli Rosetta(DE3)pLysS cells | Mus musculus | 1 | ALA3259557 | cell-based format | Scientific Literature | |
8. | ALA3267128 | B | Inhibition of Syrian hamster NAT2 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's method | Mesocricetus auratus | 1 | ALA3259557 | single protein format | Scientific Literature |