# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3266816 | A | Cytotoxicity against human HepG2.2.15 cells by MTT assay | Homo sapiens | 51 | cell-based format | Scientific Literature | ||
2. | ALA3266817 | F | Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibition of hepatitis B surface antigen secretion by ELISA | Hepatitis B virus | 41 | organism-based format | Scientific Literature | ||
3. | ALA3267145 | F | Selectivity index, ratio of CC50 for human HepG2.2.15 cells to IC50 for HBV infected in human HepG2.2.15 cells assessed as inhibition of hepatitis B surface antigen secretion | 15 | cell-based format | Scientific Literature | |||
4. | ALA3267146 | F | Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibition of hepatitis B e antigen secretion by ELISA | Hepatitis B virus | 43 | organism-based format | Scientific Literature | ||
5. | ALA3267147 | F | Selectivity index, ratio of CC50 for human HepG2.2.15 cells to IC50 for HBV infected in human HepG2.2.15 cells assessed as inhibition of hepatitis B e antigen secretion | 19 | cell-based format | Scientific Literature | |||
6. | ALA3267148 | F | Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibition of DNA replication | Hepatitis B virus | 50 | organism-based format | Scientific Literature | ||
7. | ALA3267149 | F | Selectivity index, ratio of CC50 for human HepG2.2.15 cells to IC50 for HBV infected in human HepG2.2.15 cells assessed as inhibition of DNA replication | 40 | cell-based format | Scientific Literature | |||
8. | ALA3428783 | B | Binding affinity to 6His-tagged recombinant human NF-kappaB p50 N-terminal domain expressed in Escherichia coli BL21 (DE3) at 4:1 compound to protein molar ratio after 2 hrs by mass spectrometric analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA3428787 | B | Inhibition of TNF-alpha-stimulated NF-kappaB p50 (unknown origin) expressed in HEK293 cells preincubated for 4 hrs followed by TNF-alpha challenge measured after 24 hrs by secreted alkaline phosphatase reporter assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA3428789 | A | Cytotoxicity against human Jurkat T cells assessed as appearance of early apoptotic cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
11. | ALA3428790 | A | Cytotoxicity against human Jurkat T cells assessed as appearance of late apoptotic cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
12. | ALA3428791 | A | Cytotoxicity against human Jurkat T cells assessed as appearance of necrotic cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
13. | ALA3428792 | A | Cytotoxicity against human Jurkat T cells assessed as appearance of viable cells at 25 uM after 24 hrs by annexin V-FLUOS/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
14. | ALA4341749 | F | Antiinflammatory activity in mouse BV2 cells assessed as reduction in LPS-induced NO production at 20 uM incubated for 24 hrs by Griess method | Mus musculus | 13 | cell-based format | Scientific Literature | ||
15. | ALA4341750 | P | Lipophilicity, log P of the compound | 12 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA4341751 | F | Antiinflammatory activity in mouse BV2 cells assessed as reduction in LPS-induced NO production incubated for 24 hrs by Griess method | Mus musculus | 2 | cell-based format | Scientific Literature | ||
17. | ALA4341752 | F | Antiinflammatory activity in LPS-induced mouse BV2 cells assessed as reduction in iNOS mRNA expression at 20 uM incubated for 24 hrs by RT-PCR analysis method | Mus musculus | 2 | cell-based format | Scientific Literature | ||
18. | ALA4341753 | F | Antiinflammatory activity in LPS induced mouse BV2 cells assessed as reduction in iNOS expression at 20 uM incubated for 24 hrs by DAPI based fluorescence microscopic method | Mus musculus | 2 | cell-based format | Scientific Literature | ||
19. | ALA4341754 | F | Antiinflammatory activity in LPS induced mouse BV2 cells assessed as reduction in TNFalpha incubated for 6 hrs by ELISA method | Mus musculus | 2 | cell-based format | Scientific Literature | ||
20. | ALA4341755 | F | Antiinflammatory activity in LPS induced mouse BV2 cells assessed as reduction in IL-6 incubated for 24 hrs by ELISA method | Mus musculus | 2 | cell-based format | Scientific Literature |