# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA644833 | B | In vitro inhibition of human acetylcholinesterase. | 20 | ALA1125532 | single protein format | Scientific Literature | ||
2. | ALA654880 | B | In vitro inhibition of human butryl cholinesterase. | 19 | ALA1125532 | single protein format | Scientific Literature | ||
3. | ALA654881 | B | Ratio of IC50(BChE-I) to IC50(AChE-I) | 17 | ALA1125532 | protein format | Scientific Literature | ||
4. | ALA730742 | F | Effect on brain acetylcholine concentration in mice after intraperitoneal administration of 40% lethal dose (68 mg/kg) | Mus musculus | 1 | ALA1125532 | organism-based format | Scientific Literature | |
5. | ALA730744 | F | Effect on brain acetylcholine concentration in mice after intraperitoneal administration of 60% lethal dose (102 mg/kg) | Mus musculus | 2 | ALA1125532 | organism-based format | Scientific Literature | |
6. | ALA726339 | F | Effect on brain acetylcholine concentration in mice after intraperitoneal administration of 80% lethal dose (140 mg/kg) | Mus musculus | 1 | ALA1125532 | organism-based format | Scientific Literature | |
7. | ALA742504 | A | Approximate lethal dose in mice. | Mus musculus | 19 | ALA1125532 | organism-based format | Scientific Literature | |
8. | ALA745334 | F | Percent change in brain Acetylcholine content in the mouse brain using GC/MS methodology. | Mus musculus | 16 | ALA1125532 | organism-based format | Scientific Literature | |
9. | ALA748231 | B | Ratio of IC50 (muscarinic acetylcholine receptor M2) to IC50 (muscarinic acetylcholine receptor M1) | Rattus norvegicus | 16 | ALA1125532 | assay format | Scientific Literature | |
10. | ALA746425 | B | Binding affinity against mouse muscarinic acetylcholine receptor M1 using cerebral cortex and [3H]pirenzepine | 2 | ALA1125532 | tissue-based format | Scientific Literature | ||
11. | ALA744482 | B | Ability to displace [3H]methylscopolamine ([3H]NMS) from mouse cerebral cortex | Mus musculus | 5 | ALA1125532 | tissue-based format | Scientific Literature | |
12. | ALA744484 | B | Ability to displace [3H]oxotremorine ([3H]-OXO-M) from mouse cerebral cortex | Mus musculus | 6 | ALA1125532 | tissue-based format | Scientific Literature | |
13. | ALA744485 | B | Ratio of Ki of [3H]-NMS binding to that of [3H]OXO-M binding. | Mus musculus | 6 | ALA1125532 | single protein format | Scientific Literature | |
14. | ALA744021 | B | Inhibition of [3H]N-methylscopolamine to rat muscarinic acetylcholine receptor M2 from heart tissue | Rattus norvegicus | 14 | ALA1125532 | single protein format | Scientific Literature | |
15. | ALA846890 | F | Concentration required to potentiate the contraction of isolated rat ileum produced by 1 x 10 e -7 M Ach by 20 % | Rattus norvegicus | 13 | ALA1125532 | organism-based format | Scientific Literature |