# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA635959 | Physicochemical | Partition coefficient (logD7.4) | 8 | ALA1121902 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA649671 | Binding | Apparent pA2 value for isoproterenol-induced vasodilation (beta2) evaluated against beta-2 adrenergic receptor in anesthetized dogs | Canis lupus familiaris | 1 | ALA1123020 | single protein format | Scientific Literature | |
3. | ALA646925 | Functional | Beta adrenergic receptor antagonist potency relative to propranolol. | 8 | ALA1121902 | assay format | Scientific Literature | ||
4. | ALA647666 | Binding | Apparent pA2 value for blockade of isoproterenol-induced increase in heart rate evaluated against beta adrenergic receptor in anesthetized dogs | Canis lupus familiaris | 2 | ALA1123020 | tissue-based format | Scientific Literature | |
5. | ALA652296 | Functional | Compound was evaluated for competitive antagonism of beta-2 adrenergic receptor in rat uterus measured as pA2 (-log KB) | 3 | ALA1122684 | tissue-based format | Scientific Literature | ||
6. | ALA654265 | Binding | Apparent pA2 value for myocardial contractile force (beta-1) evaluated against beta-1 adrenergic receptor in anesthetized dogs | Canis lupus familiaris | 2 | ALA1123020 | single protein format | Scientific Literature | |
7. | ALA655647 | Functional | Compound was evaluated for competitive antagonism of beta-1 adrenergic receptor in guinea pig atria measured as pA2 (-log KB) | Cavia porcellus | 3 | ALA1122684 | assay format | Scientific Literature | |
8. | ALA668577 | Functional | Concentration required to decrease hindlimb perfusion pressure(55 mmHg) in anesthetized dogs after intra arterial administration. | Canis lupus familiaris | 8 | ALA1121902 | organism-based format | Scientific Literature | |
9. | ALA667670 | Functional | Vasodilator potency relative to propranolol. | Canis lupus familiaris | 8 | ALA1121902 | organism-based format | Scientific Literature | |
10. | ALA668341 | Functional | Compound was tested for its ability to block isoproterenol-induced contractile force in anesthetized dogs. | Canis lupus familiaris | 8 | ALA1121902 | organism-based format | Scientific Literature | |
11. | ALA668342 | Functional | Compound was tested for its ability to block isoproterenol-induced increases in heart rate(HR) in anesthetized dogs. | Canis lupus familiaris | 8 | ALA1121902 | organism-based format | Scientific Literature | |
12. | ALA879852 | Functional | Compound was tested for its ability to block isoproterenol-induced vasodilation in anesthetized dogs. | Canis lupus familiaris | 8 | ALA1121902 | organism-based format | Scientific Literature | |
13. | ALA3252774 | Functional | Antiarrhythmic activity in New Zealand White rabbit isolated atria assessed as reduction of maximum driving frequency after 15 mins | Oryctolagus cuniculus | 11 | ALA3243947 | tissue-based format | Scientific Literature | |
14. | ALA3252776 | ADME | Negative inotropic activity in New Zealand White rabbit isolated atria assessed as reduction of tissue contractility after 15 mins | Oryctolagus cuniculus | 11 | ALA3243947 | assay format | Scientific Literature | |
15. | ALA3252778 | Unassigned | Selectivity index, ratio of pED40 for tissue contractility to pED40 for maximum driving response in New Zealand White rabbit isolated atria | Oryctolagus cuniculus | 11 | ALA3243947 | assay format | Scientific Literature | |
16. | ALA3252779 | Physicochemical | Octanol-phosphate buffer partition coefficient, log P of the compound | 12 | ALA3243947 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA3529400 | ADME | Unbound hepatobiliary clearance in human treated with propranolol | Homo sapiens | 1 | ALA3526022 | organism-based format | Scientific Literature | |
18. | ALA3529401 | ADME | Unbound renal clearance in human treated with propranolol | Homo sapiens | 1 | ALA3526022 | organism-based format | Scientific Literature | |
19. | ALA3529402 | ADME | Fraction unbound in human treated with propranolol | Homo sapiens | 1 | ALA3526022 | organism-based format | Scientific Literature | |
20. | ALA3529403 | ADME | Systemic clearance in human treated with propranolol | Homo sapiens | 1 | ALA3526022 | organism-based format | Scientific Literature |