# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3268596 | Binding | Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane at 10 nM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 14 | ALA3259629 | tissue-based format | Scientific Literature | |
2. | ALA3268597 | Binding | Inhibition of mouse brain FAAH at 10 uM after 30 mins by FP-rhodamine ABPP-based mass spectrometry relative to control | Mus musculus | 9 | ALA3259629 | assay format | Scientific Literature | |
3. | ALA3268605 | Binding | Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane at 1 nM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 9 | ALA3259629 | tissue-based format | Scientific Literature | |
4. | ALA3268606 | Binding | Inhibition of FP-rhodamine-labelled recombinant mouse DAGLbeta expressed in HEK293T cells at 1 uM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 9 | ALA3259629 | cell-based format | Scientific Literature | |
5. | ALA3268610 | Binding | Inhibition of FP-rhodamine-labelled recombinant mouse LYPLA1 at 10 uM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 7 | ALA3259629 | single protein format | Scientific Literature | |
6. | ALA3268611 | Binding | Inhibition of FP-rhodamine-labelled recombinant mouse LYPLA2 at 10 uM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 7 | ALA3259629 | single protein format | Scientific Literature | |
7. | ALA3268613 | Binding | Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 3 | ALA3259629 | tissue-based format | Scientific Literature | |
8. | ALA3268614 | Binding | Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measured after 30 mins by LC-MS analysis | Mus musculus | 3 | ALA3259629 | cell-based format | Scientific Literature | |
9. | ALA3268615 | Binding | In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay | Mus musculus | 3 | ALA3259629 | cell-based format | Scientific Literature | |
10. | ALA3268616 | Binding | In situ inhibition of ABHD6 in mouse Neuro2a cells at 3 nM after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis | Mus musculus | 3 | ALA3259629 | cell-based format | Scientific Literature | |
11. | ALA3268617 | Functional | In vivo inhibition of ABHD6 in C57Bl/6 mouse liver at 1 mg/kg, ip after 4 hrs by HT-10-labelled gel-based competitive ABPP assay | Mus musculus | 2 | ALA3259629 | organism-based format | Scientific Literature | |
12. | ALA3268618 | Functional | In vivo inhibition of ABHD6 in C57Bl/6 mouse liver at 0.1 mg/kg, ip after 4 hrs by HT-10-labelled gel-based competitive ABPP assay | Mus musculus | 2 | ALA3259629 | organism-based format | Scientific Literature | |
13. | ALA3268619 | Functional | In vivo inhibition of ABHD6 in C57Bl/6 mouse brain at 1 mg/kg, ip after 4 hrs by HT-10-labelled gel-based competitive ABPP assay | Mus musculus | 1 | ALA3259629 | organism-based format | Scientific Literature | |
14. | ALA3268621 | Functional | In vivo inhibition of carboxylesterase-1 in C57Bl/6 mouse liver at 0.1 to 1 mg/kg, ip after 4 hrs by FP-rhodamine-labelled gel-based competitive ABPP assay | Mus musculus | 2 | ALA3259629 | organism-based format | Scientific Literature | |
15. | ALA3268622 | Functional | In vivo inhibition of carboxylesterase-1 in C57Bl/6 mouse brain at 0.1 to 1 mg/kg, ip after 4 hrs by FP-rhodamine-labelled gel-based competitive ABPP assay | Mus musculus | 2 | ALA3259629 | organism-based format | Scientific Literature | |
16. | ALA3268623 | Functional | In vivo inhibition of ABHD6 in C57Bl/6 mouse brain at 40 mg/kg, ip after 4 hrs by FP-rhodamine/HT-10-labelled gel-based competitive assay | Mus musculus | 1 | ALA3259629 | organism-based format | Scientific Literature | |
17. | ALA3269001 | Functional | In vivo inhibition of ABHD6 in C57Bl/6 mouse liver at 20 mg/kg, ip after 4 hrs by FP-rhodamine/HT-10-labelled gel-based competitive assay | Mus musculus | 3 | ALA3259629 | organism-based format | Scientific Literature | |
18. | ALA3269004 | Functional | In vivo inhibition of FAAH in C57Bl/6 mouse liver at =>10 mg/kg, po after 4 hrs by FP-rhodamine/HT-10-labelled gel-based competitive assay | Mus musculus | 2 | ALA3259629 | organism-based format | Scientific Literature | |
19. | ALA3269006 | Binding | Inhibition of Aadacl1 in mouse Neuro2a cells at 3 nM after 4 hrs by ABPP-SILAC assay | Mus musculus | 3 | ALA3259629 | cell-based format | Scientific Literature | |
20. | ALA3269007 | Binding | In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis | Mus musculus | 3 | ALA3259629 | cell-based format | Scientific Literature |