Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane at 10 nM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay
Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane at 1 nM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay
Inhibition of FP-rhodamine-labelled recombinant mouse DAGLbeta expressed in HEK293T cells at 1 uM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay
Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay
Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measured after 30 mins by LC-MS analysis
In vivo inhibition of carboxylesterase-1 in C57Bl/6 mouse liver at 0.1 to 1 mg/kg, ip after 4 hrs by FP-rhodamine-labelled gel-based competitive ABPP assay
In vivo inhibition of carboxylesterase-1 in C57Bl/6 mouse brain at 0.1 to 1 mg/kg, ip after 4 hrs by FP-rhodamine-labelled gel-based competitive ABPP assay
In vivo inhibition of DAGLbeta in C57Bl/6 mouse liver and bain at 0.1 to 1 mg/kg, ip after 4 hrs by FP-rhodamine-labelled gel-based competitive ABPP assay
In vivo inhibition of PLA2G7 in C57Bl/6 mouse liver and bain at 0.1 to 1 mg/kg, ip after 4 hrs by FP-rhodamine-labelled gel-based competitive ABPP assay