# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3270557 | A | Oral bioavailability in immature Sprague-Dawley rat at 0.5 mg/kg | Rattus norvegicus | 2 | ALA3259738 | organism-based format | Scientific Literature | |
2. | ALA3270558 | F | Positive allosteric modulation of human FSH receptor expressed in CHO cells assessed as effect on FSH-induced cAMP accumulation after 1 hr by HTRF assay | Homo sapiens | 23 | ALA3259738 | cell-based format | Scientific Literature | |
3. | ALA3270561 | A | Clearance in rat microsomes | Rattus norvegicus | 7 | ALA3259738 | assay format | Scientific Literature | |
4. | ALA3270562 | A | Clearance in human microsomes | Homo sapiens | 7 | ALA3259738 | assay format | Scientific Literature | |
5. | ALA3270563 | F | Induction of estradiol production in rat primary granulosa cells after 24 hrs by ELISA | Rattus norvegicus | 2 | ALA3259738 | assay format | Scientific Literature | |
6. | ALA3270926 | F | Induction of estradiol production in rat primary granulosa cells after 24 hrs by ELISA relative to FSH | Rattus norvegicus | 2 | ALA3259738 | assay format | Scientific Literature | |
7. | ALA3270927 | A | Clearance in immature Sprague-Dawley rat at 0.2 mg/kg, iv | Rattus norvegicus | 2 | ALA3259738 | organism-based format | Scientific Literature | |
8. | ALA3270928 | A | Volume of distribution at steady state in immature Sprague-Dawley rat at 0.2 mg/kg, iv | Rattus norvegicus | 2 | ALA3259738 | organism-based format | Scientific Literature | |
9. | ALA3270929 | P | Aqueous solubility of the compound at pH 7.4 | 1 | ALA3259738 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA3270930 | B | Selectivity ratio of LHR (unknown origin) to human FSH receptor expressed in CHO cells | Homo sapiens | 2 | ALA3259738 | cell-based format | Scientific Literature | |
11. | ALA3270931 | B | Selectivity ratio of TSHR (unknown origin) to human FSH receptor expressed in CHO cells | Homo sapiens | 2 | ALA3259738 | cell-based format | Scientific Literature | |
12. | ALA3812618 | F | Positive allosteric modulation of FSHR (unknown origin) expressed in CHO cells assessed as FSH-induced cAMP accumulation incubated for 1 hr by HTRF assay | Homo sapiens | 6 | ALA3808353 | cell-based format | Scientific Literature | |
13. | ALA3812619 | B | Positive allosteric modulation of human FSHR expressed in rat granulocytes assessed as FSH-induced estradiol production after 72 hrs by radioimmunossay | Homo sapiens | 4 | ALA3808353 | cell-based format | Scientific Literature |