#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3268036	F	Antiproliferative activity against human HeLa cells assessed as cell viability after 96 hrs by CellTiter96 assay	Homo sapiens	25		cell-based format	Scientific Literature
2.	ALA3268037	F	Antiproliferative activity against human K562 cells assessed as cell viability after 96 hrs by CellTiter96 assay	Homo sapiens	25		cell-based format	Scientific Literature
3.	ALA3268038	F	Antiproliferative activity against human MDA-MB-468 cells assessed as cell viability after 96 hrs by CellTiter96 assay	Homo sapiens	25		cell-based format	Scientific Literature
4.	ALA3268039	F	Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 96 hrs by CellTiter96 assay	Homo sapiens	25		cell-based format	Scientific Literature
5.	ALA3268040	A	AUC in Sprague-Dawley rat at 2 mg/kg, iv compound formulated with 5% DMSO, 10% cremophor and 85% water by LC-MS/MS analysis	Rattus norvegicus	5		organism-based format	Scientific Literature
6.	ALA3268041	A	Volume of distribution in Sprague-Dawley rat at 2 mg/kg, iv compound formulated with 5% DMSO, 10% cremophor and 85% water by LC-MS/MS analysis	Rattus norvegicus	5		organism-based format	Scientific Literature
7.	ALA3268042	A	Clearance in Sprague-Dawley rat at 2 mg/kg, iv compound formulated with 5% DMSO, 10% cremophor and 85% water by LC-MS/MS analysis	Rattus norvegicus	5		organism-based format	Scientific Literature
8.	ALA3268043	A	Oral bioavailability in Sprague-Dawley rat at 20 mg/kg compound formulated with 1% methylcellulose in water by LC-MS/MS analysis	Rattus norvegicus	5		organism-based format	Scientific Literature
9.	ALA3268044	A	Oral bioavailability in Sprague-Dawley rat at 20 mg/kg compound formulated with 5% DMSO, 10% cremophor and 85% water by LC-MS/MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
10.	ALA3268045	P	Solubility of the compound in phosphate buffered saline containing 1% DMSO at pH 7.4 after 2 hrs by HPLC analysis		2		small-molecule physicochemical format	Scientific Literature
11.	ALA3268046	A	Half life in rat liver microsomes at 1 uM by LC-MS/MS analysis	Rattus norvegicus	2		assay format	Scientific Literature
12.	ALA3268047	F	Antitumor activity against human MDA-MB-231 cells xenografted in BALB/c nu/nu mouse assessed as tumor volume at 20 mg/kg, iv qd for 28 days relative to control	Homo sapiens	1		organism-based format	Scientific Literature
13.	ALA3268048	F	Antitumor activity against human MDA-MB-231 cells xenografted in BALB/c nu/nu mouse assessed as tumor volume at 150 mg/kg, po bid for 28 days administered via gavage relative to control	Homo sapiens	1		organism-based format	Scientific Literature
14.	ALA3268049	T	Toxicity in BALB/c nu/nu mouse xenografted with human MDA-MB-231 cells assessed as body weight loss at 20 mg/kg, iv qd for 28 days	Mus musculus	1		organism-based format	Scientific Literature
15.	ALA3268050	T	Toxicity in BALB/c nu/nu mouse xenografted with human MDA-MB-231 cells assessed as body weight loss at 150 mg/kg, po bid for 28 days	Mus musculus	1		organism-based format	Scientific Literature
16.	ALA3268051	B	Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as reduction in coimmunoprecipitated Hec1 level at 100 nM after 16 hrs by co-immunoprecipitation assay	Homo sapiens	1		cell-based format	Scientific Literature
17.	ALA3268052	B	Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as induction of Nek2 degradation after 24 hrs by western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
18.	ALA3268053	B	Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as induction of Nek2 degradation at 10 nM after 24 hrs by western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
19.	ALA3268054	B	Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as reduction in Hec1 level at 100 nM by western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
20.	ALA3268055	B	Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as induction of Nek2 degradation at 100 nM by western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature