# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3269580 | F | Antiinflammatory activity in Wistar albino rat assessed as inhibition of carrageenan-induced increase in paw edema at 10 mg/kg, po after 30 mins (Rvb = 30.1 %) | Rattus norvegicus | 10 | ALA3259612 | organism-based format | Scientific Literature | |
2. | ALA3269581 | F | Antiinflammatory activity in Wistar albino rat assessed as inhibition of carrageenan-induced increase in paw edema at 10 mg/kg, po after 90 mins (Rvb = 38.7 %) | Rattus norvegicus | 11 | ALA3259612 | organism-based format | Scientific Literature | |
3. | ALA3269582 | B | Inhibition of rat seminal vesicle COX-1 using arachidonic acid as substrate assessed as reduction of PGG2 to PGH2 incubated for 1 min prior to substrate addition measured after 25 secs by chromogenic assay | Rattus norvegicus | 10 | ALA3259612 | single protein format | Scientific Literature | |
4. | ALA3269583 | B | Inhibition of human recombinant COX-2 expressed in insect cell system using arachidonic acid as substrate assessed as reduction of PGG2 to PGH2 incubated for 1 min prior to substrate addition measured after 25 secs by chromogenic assay | Homo sapiens | 10 | ALA3259612 | assay format | Scientific Literature | |
5. | ALA3269584 | B | Selectivity index, ratio of IC50 for human recombinant COX-2 to IC50 for rat seminal vesicle COX-1 | 10 | ALA3259612 | tissue-based format | Scientific Literature |