# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3270664 | B | Inhibition of human recombinant 5-LO assessed as product formation at 3 uM by cell-free assay relative to control | Homo sapiens | 25 | ALA3259773 | single protein format | Scientific Literature | |
2. | ALA3270665 | B | Inhibition of 5-LO in human neutrophils assessed as product formation at 3 uM by cell-intact assay relative to control in presence of 2.5 uM A23187 ionophore | Homo sapiens | 25 | ALA3259773 | single protein format | Scientific Literature | |
3. | ALA3270666 | B | Inhibition of human recombinant 5-LO assessed as product formation by cell-free assay relative to control | Homo sapiens | 7 | ALA3259773 | single protein format | Scientific Literature | |
4. | ALA3270667 | B | Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 2.5 uM A23187 ionophore | Homo sapiens | 7 | ALA3259773 | single protein format | Scientific Literature | |
5. | ALA3270668 | B | Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 20 uM A23187/AA ionophore | Homo sapiens | 7 | ALA3259773 | single protein format | Scientific Literature | |
6. | ALA3795841 | F | Antiproliferative activity against human LoVo cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
7. | ALA3795842 | F | Antiproliferative activity against apoptosis resistant human U373 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
8. | ALA3795843 | F | Antiproliferative activity against apoptosis resistant human A549 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
9. | ALA3795844 | F | Antiproliferative activity against apoptosis resistant human OE21 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
10. | ALA3795845 | F | Antiproliferative activity against apoptosis resistant human SK-MEL-28 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
11. | ALA3795846 | F | Antiproliferative activity against apoptosis sensitive human Hs683 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
12. | ALA3795847 | F | Antiproliferative activity against apoptosis sensitive mouse B16F10 cells after 72 hrs by MTT assay | Mus musculus | 21 | ALA3792301 | cell-based format | Scientific Literature | |
13. | ALA3795848 | F | Antiproliferative activity against apoptosis sensitive human PC3 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
14. | ALA3795849 | F | Antiproliferative activity against apoptosis sensitive human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 21 | ALA3792301 | cell-based format | Scientific Literature | |
15. | ALA4042004 | F | Cytotoxicity against human KCL22 cells assessed as reduction in cell viability at 1 uM after 48 hrs by MTS assay | Homo sapiens | 62 | ALA4041496 | cell-based format | Scientific Literature | |
16. | ALA4042005 | F | Cytotoxicity against human KCL22 cells harboring ABL1 T315I mutant assessed as reduction in cell viability at 1 uM after 48 hrs by MTS assay | Homo sapiens | 62 | ALA4041496 | cell-based format | Scientific Literature | |
17. | ALA5233127 | F | Antibacterial activity against Klebsiella pneumoniae B9 assessed as inhibition of bacterial growth incubated for 16 hrs by broth microdilution method | Klebsiella pneumoniae | 31 | ALA5230178 | organism-based format | Scientific Literature | |
18. | ALA5233128 | F | Potentiation of colistin-induced antibacterial activity against colistin resistant Klebsiella pneumoniae B9 assessed as colistin MIC at 5 uM incubated for 16 hrs by broth microdilution method | Klebsiella pneumoniae | 30 | ALA5230178 | organism-based format | Scientific Literature |