# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3271043 | F | Neuroprotective activity in wild type C57BL/J6 mouse assessed as survival of newborn hippocampal neurons at 0.1 to 10 uM, icv administered for 7 days by BrdU staining-based microscopy relative to vehicle-treated control | Mus musculus | 3 | ALA3259666 | organism-based format | Scientific Literature | |
2. | ALA3271044 | F | Neuroprotective activity in substantia nigra of C57Bl/6 mouse neurogenesis model assessed as protection from MPTP-induced cell death in mature neurons at 5 mg/kg/day, ip bid administered for 21 days by immunohistochemical analysis relative to vehicle-treated control | Mus musculus | 3 | ALA3259666 | organism-based format | Scientific Literature | |
3. | ALA3265917 | A | Cytotoxicity against human NCI-H2122 cells | Homo sapiens | 1 | ALA3259666 | cell-based format | Scientific Literature | |
4. | ALA3265918 | A | Cytotoxicity against human NCI-H2009 cells | Homo sapiens | 1 | ALA3259666 | cell-based format | Scientific Literature | |
5. | ALA3265919 | A | Cytotoxicity against human HCC44 cells | Homo sapiens | 1 | ALA3259666 | cell-based format | Scientific Literature | |
6. | ALA3266304 | B | Inhibition of human ERG channel at 50 uM by patch clamp technique | Homo sapiens | 1 | ALA3259666 | assay format | Scientific Literature | |
7. | ALA3266305 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
8. | ALA3266306 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
9. | ALA3266307 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
10. | ALA3266308 | A | Inhibition of CYP2C8 (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
11. | ALA3266309 | A | Inhibition of CYP2B6 (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
12. | ALA3266310 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
13. | ALA3266311 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
14. | ALA3266312 | A | Protein binding in plasma (unknown origin) by ultracentrifugation method | Not specified | 1 | ALA3259666 | cell-free format | Scientific Literature | |
15. | ALA3266313 | B | Inhibition of mu opioid receptor (unknown origin) | Homo sapiens | 1 | ALA3259666 | single protein format | Scientific Literature | |
16. | ALA3266314 | B | Inhibition of TSPO (unknown origin) | Homo sapiens | 3 | ALA3259666 | single protein format | Scientific Literature | |
17. | ALA3266321 | F | Neuroprotective activity in wild type C57BL/J6 mouse assessed as survival of newborn hippocampal neurons at 10 uM, icv administered for 7 days by BrdU staining-based microscopy relative to vehicle-treated control | Mus musculus | 2 | ALA3259666 | organism-based format | Scientific Literature |