| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3271206 | B | Inhibition of Isoleucine-tRNA synthetase in wild type Escherichia coli S30 cell extract assessed as inhibition of [C14]isoleucine incorporation in tRNA under in vitro aminoacylation conditions at 3.13 uM by liquid scintillation counting | Escherichia coli | 7 | assay format | Scientific Literature | ||
| 2. | ALA3271209 | F | Antibacterial activity against wild type Escherichia coli assessed as growth inhibition in Luria broth at 5 mM after 8 to 18 hrs by disc diffusion method | Escherichia coli | 7 | organism-based format | Scientific Literature | ||
| 3. | ALA4394779 | B | Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assay | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature | ||
| 4. | ALA4394781 | B | Inhibition of ileRS in Escherichia coli NCIB 8743 S30 extract assessed as aminoacylation at 250 nM incubated for 5 mins in presence of 14C-labeled isoleucine by liquid scintillation counting method relative to control | Escherichia coli | 4 | single protein format | Scientific Literature | ||
| 5. | ALA4394782 | A | Stability of compound in Escherichia coli NCIB 8743 S30 extract assessed as compound degradation incubated for 1 hr n presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli | 4 | subcellular format | Scientific Literature | ||
| 6. | ALA4394783 | A | Stability of compound in Escherichia coli NCIB 8743 S30 extract assessed as compound degradation incubated for 48 hr in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli | 4 | subcellular format | Scientific Literature | ||
| 7. | ALA4394786 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimI incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 8. | ALA4394787 | B | Inhibition of leuRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimI incubated for 5 to 60 mins in presence of 14C-labeled leucine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 9. | ALA4394788 | B | Inhibition of tyrRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimI incubated for 5 to 60 mins in presence of 14C-labeled tyrosine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 10. | ALA4394789 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing SUMO incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 11. | ALA4394790 | B | Inhibition of leuRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing SUMO incubated for 5 to 60 mins in presence of 14C-labeled leucine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 12. | ALA4394791 | B | Inhibition of tyrRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing SUMO incubated for 5 to 60 mins in presence of 14C-labeled tyrosine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
| 13. | ALA4394792 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimL incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 6 | single protein format | Scientific Literature | ||
| 14. | ALA4394793 | B | Inhibition of leuRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimL incubated for 5 to 60 mins in presence of 14C-labeled leucine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 6 | single protein format | Scientific Literature | ||
| 15. | ALA4394794 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing YhhY incubated for 5 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature | ||
| 16. | ALA4394795 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing YhhY incubated for 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature | ||
| 17. | ALA4394796 | B | Inhibition of leuRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing YhhY incubated for 5 mins in presence of 14C-labeled leucine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature | ||
| 18. | ALA4394797 | B | Inhibition of leuRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing YhhY incubated for 60 mins in presence of 14C-labeled leucine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 3 | single protein format | Scientific Literature |
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