| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3266883 | B | Displacement of Flu-BID/FAM-BID from His-tagged A1-BFL-1 (1 to 151) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence polarization assay | Homo sapiens | 7 | ALA3259780 | assay format | Scientific Literature | |
| 2. | ALA3266886 | B | Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence polarization assay | Homo sapiens | 47 | ALA3259780 | assay format | Scientific Literature | |
| 3. | ALA3266887 | B | Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal biotin-labeled BIM BH3 peptide interaction after 30 mins by surface plasmon resonance analysis | Homo sapiens | 46 | ALA3259780 | assay format | Scientific Literature | |
| 4. | ALA3266888 | B | Displacement of Flu-BID/FAM-BID from His-tagged BCL2 (1 to 202) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence polarization assay | Homo sapiens | 7 | ALA3259780 | assay format | Scientific Literature | |
| 5. | ALA3266889 | B | Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence polarization assay | Homo sapiens | 7 | ALA3259780 | assay format | Scientific Literature | |
| 6. | ALA3266890 | B | Displacement of Flu-BID/FAM-BID from His-tagged BCLX-L (1 to 209) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence polarization assay | Homo sapiens | 9 | ALA3259780 | assay format | Scientific Literature | |
| 7. | ALA3266891 | B | Selectivity ratio of Ki for His-tagged A1-BFL-1 (1 to 151) (unknown origin) to Ki for His-tagged MCL1 (171 to 327) (unknown origin) | Homo sapiens | 2 | ALA3259780 | assay format | Scientific Literature | |
| 8. | ALA3266892 | B | Selectivity ratio of Ki for His-tagged BCLW (1 to 155) (unknown origin) to Ki for His-tagged MCL1 (171 to 327) (unknown origin) | Homo sapiens | 2 | ALA3259780 | assay format | Scientific Literature | |
| 9. | ALA3266893 | B | Selectivity ratio of Ki for His-tagged BCL2 (1 to 202) (unknown origin) to Ki for His-tagged MCL1 (171 to 327) (unknown origin) | Homo sapiens | 3 | ALA3259780 | assay format | Scientific Literature | |
| 10. | ALA3266894 | B | Selectivity ratio of Ki for His-tagged BCLX-L (1 to 209) (unknown origin) to Ki for His-tagged MCL1 (171 to 327) (unknown origin) | Homo sapiens | 2 | ALA3259780 | assay format | Scientific Literature | |
| 11. | ALA3266895 | B | Inhibition of MCL1-biotin-labeled NOXA interaction in human 2LMP whole cell lysate at 100 uM by Western blotting analysis | Homo sapiens | 3 | ALA3259780 | assay format | Scientific Literature | |
| 12. | ALA3267198 | B | Inhibition of MCL1 in wild-type MEF assessed as induction of BAX/BAK-dependent cell death after 15 hrs by propidium iodide staining-based flow cytometric analysis | Mus musculus | 1 | ALA3259780 | single protein format | Scientific Literature | |
| 13. | ALA3267199 | B | Inhibition of MCL1 in BAX/BAK double knock out MEF assessed as induction of cell death at 16 uM after 15 hrs by propidium iodide staining-based flow cytometric analysis relative to control | Mus musculus | 1 | ALA3259780 | single protein format | Scientific Literature | |
| 14. | ALA3267200 | B | Inhibition of MCL1 in wild-type MEF assessed as induction of BAX/BAK-dependent cell death at 16 uM after 15 hrs by propidium iodide staining-based flow cytometric analysis relative to control | Mus musculus | 1 | ALA3259780 | single protein format | Scientific Literature | |
| 15. | ALA3267201 | B | Inhibition of MCL1 (unknown origin) overexpressed in E-mu-myc transgenic mouse lymphoma cells assessed as induction of cell death after 15 to 18 hrs by flow cytometric analysis | Homo sapiens | 3 | ALA3259780 | cell-based format | Scientific Literature | |
| 16. | ALA3267202 | B | Inhibition of BCL2 (unknown origin) overexpressed in E-mu-myc transgenic mouse lymphoma cells assessed as induction of cell death after 15 to 18 hrs by flow cytometric analysis | Homo sapiens | 3 | ALA3259780 | cell-based format | Scientific Literature | |
| 17. | ALA3267205 | F | Cytotoxicity against human HL60 cells assessed as intracellular ATP level after 3 days by CellTiterGlo assay | Homo sapiens | 9 | ALA3259780 | cell-based format | Scientific Literature | |
| 18. | ALA3267206 | F | Cytotoxicity against human MV4-11 cells assessed as intracellular ATP level after 3 days by CellTiterGlo assay | Homo sapiens | 9 | ALA3259780 | cell-based format | Scientific Literature | |
| 19. | ALA3267207 | F | Cytotoxicity against human K562 cells assessed as intracellular ATP level after 3 days by CellTiterGlo assay | Homo sapiens | 9 | ALA3259780 | cell-based format | Scientific Literature | |
| 20. | ALA3267208 | F | Induction of apoptosis in human HL60 cells after 20 hrs by by annexin V-FITC and propidium iodide staining-based flow cytometric analysis | Homo sapiens | 2 | ALA3259780 | cell-based format | Scientific Literature |
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