# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3265473 | B | Inhibition of bovine erythrocytes AChE using acetylthiocholine as substrate by UV spectroscopic analysis | Bos taurus | 12 | ALA3259644 | assay format | Scientific Literature | |
2. | ALA3265474 | B | Inhibition of horse serum BuChE using butyrylthiocholine as substrate by UV spectroscopic analysis | Equus caballus | 12 | ALA3259644 | single protein format | Scientific Literature | |
3. | ALA3265475 | P | Permeability of the compound by PAMPA | 12 | ALA3259644 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA3265476 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 3 uM after 24 hrs by lactate dehydrogenase release assay | Homo sapiens | 11 | ALA3259644 | cell-based format | Scientific Literature | |
5. | ALA3265477 | F | Neuroprotective activity in human SH-SY5Y cells assessed as protection against rotenone-oligomycin-induced toxicity at 0.3 uM preincubated for 24 hrs before rotenone-oligomycin addition measured after 24 hrs by lactate dehydrogenase release assay | Homo sapiens | 12 | ALA3259644 | cell-based format | Scientific Literature | |
6. | ALA3265478 | F | Neuroprotective activity in human SH-SY5Y cells assessed as protection against rotenone-oligomycin-induced toxicity at 1 uM preincubated for 24 hrs before rotenone-oligomycin addition measured after 24 hrs by lactate dehydrogenase release assay | Homo sapiens | 12 | ALA3259644 | cell-based format | Scientific Literature | |
7. | ALA3265479 | F | Neuroprotective activity in human SH-SY5Y cells assessed as protection against rotenone-oligomycin-induced toxicity at 3 uM preincubated for 24 hrs before rotenone-oligomycin addition measured after 24 hrs by lactate dehydrogenase release assay | Homo sapiens | 12 | ALA3259644 | cell-based format | Scientific Literature | |
8. | ALA3265480 | F | Neuroprotective activity in human SH-SY5Y cells assessed as protection against rotenone-oligomycin-induced toxicity at 0.3 uM co-incubated with rotenone-oligomycin measured after 24 hrs by lactate dehydrogenase release assay | Homo sapiens | 12 | ALA3259644 | cell-based format | Scientific Literature | |
9. | ALA3265481 | F | Neuroprotective activity in human SH-SY5Y cells assessed as protection against rotenone-oligomycin-induced toxicity at 1 uM co-incubated with rotenone-oligomycin measured after 24 hrs by lactate dehydrogenase release assay | Homo sapiens | 12 | ALA3259644 | cell-based format | Scientific Literature | |
10. | ALA3265482 | F | Neuroprotective activity in human SH-SY5Y cells assessed as protection against rotenone-oligomycin-induced toxicity at 3 uM co-incubated with rotenone-oligomycin measured after 24 hrs by lactate dehydrogenase release assay | Homo sapiens | 12 | ALA3259644 | cell-based format | Scientific Literature | |
11. | ALA3265483 | F | Antioxidant activity in human SH-SY5Y cells assessed as rotenone-oligomycin-induced sequestering of mitochondrial free radicals at 0.3 uM after 120 mins using DCFH-DA by fluorescence microplate reader analysis | Homo sapiens | 6 | ALA3259644 | cell-based format | Scientific Literature | |
12. | ALA3265484 | B | Inhibition of calcium channel in human SH-SY5Y cells assessed as blockade of K+-evoked cytosolic calcium increase at 3 uM after 15 mins using Fluo-4/AM by fluorescence microplate reader analysis | Homo sapiens | 6 | ALA3259644 | cell-based format | Scientific Literature |