Antiviral activity against Encephalomyocarditis virus infected in CF-1 mouse assessed as host survival time ratio at 10 mg/kg, sc administered 28, 22, 2 hrs before and 2 hrs after virus inoculation
Antiviral activity against Encephalomyocarditis virus infected in CF-1 mouse assessed as host survival time ratio at 50 mg/kg, sc administered 28, 22, 2 hrs before and 2 hrs after virus inoculation
Antiviral activity against Encephalomyocarditis virus infected in CF-1 mouse assessed as host survival time ratio at 250 mg/kg, sc administered 28, 22, 2 hrs before and 2 hrs after virus inoculation
Antiviral activity against Encephalomyocarditis virus infected in CF-1 mouse assessed as host survival time ratio at 50 mg/kg, po administered via gavage at 28, 22, 2 hrs before and 2 hrs after virus inoculation
Antiviral activity against Encephalomyocarditis virus infected in CF-1 mouse assessed as host survival time ratio at 250 mg/kg, po administered via gavage as single dose at 22 to 28 hrs before virus inoculation
In vitro antiviral activity against Herpesvirus hominis type 1 infected in African green monkey Vero cells assessed as log reduction of virus titer by cytopathologic assay (Rvb = 5)
In vivo antiviral activity against Herpesvirus hominis type 1 infected in hairless mouse assessed as suppression of ulcerated zoster-like lesions development administered topically at 2, 4 and 6 hrs after virus inoculation followed by continuous treatment daily for 4 days four times a day at 2 hrs interval measured on 8th day post-infection
In vivo antiviral activity against Herpesvirus hominis type 1 infected in hairless mouse assessed as decrease in lesion score administered topically at 2, 4 and 6 hrs after virus inoculation followed by continuous treatment daily for 4 days four times a day at 2 hrs interval measured on 8th day post-infection