# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3282199 | Physicochemical | Dissociation constant, pKa of the compound in 0.01 M potassium hydrogen phthalate | 17 | ALA3272033 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3282200 | ADME | Drug absorption in buccal cavity in human at pH 9.3 after 5 mins by UV spectrometry | Homo sapiens | 21 | ALA3272033 | organism-based format | Scientific Literature | |
3. | ALA3282201 | ADME | Drug absorption in buccal cavity in human at pH 5.50 after 5 mins by UV spectrometry | Homo sapiens | 21 | ALA3272033 | organism-based format | Scientific Literature | |
4. | ALA3282202 | ADME | Drug absorption in buccal cavity in human at pH 7.50 after 5 mins by UV spectrometry | Homo sapiens | 21 | ALA3272033 | organism-based format | Scientific Literature | |
5. | ALA3282203 | ADME | Drug absorption in buccal cavity in human at pH 9.30 after 5 mins by UV spectrometry | Homo sapiens | 21 | ALA3272033 | organism-based format | Scientific Literature | |
6. | ALA3282216 | Functional | Antiarrhythmic activity in Hartley guinea pig atria assessed as change in maximum driving rate at 73.2 uM/l after 5 mins | Cavia porcellus | 1 | ALA3272033 | tissue-based format | Scientific Literature | |
7. | ALA3282217 | Functional | Antiarrhythmic activity in Hartley guinea pig atria assessed as change in maximum driving rate at 36.6 uM/l after 5 mins | Cavia porcellus | 1 | ALA3272033 | tissue-based format | Scientific Literature | |
8. | ALA3282218 | Functional | Antiarrhythmic activity in ip dosed Swiss-Webster albino mouse assessed as prevention of chloroform-induced ventricular fibrillation | Mus musculus | 22 | ALA3272033 | organism-based format | Scientific Literature | |
9. | ALA3282219 | Toxicity | Toxicity in ip dosed Swiss-Webster albino mouse | Mus musculus | 22 | ALA3272033 | organism-based format | Scientific Literature | |
10. | ALA3282220 | ADME | Therapeutic index, ratio of LD50 for toxicity to ED50 for antiarrhythmic activity in ip dosed Swiss-Webster albino mouse | Mus musculus | 22 | ALA3272033 | organism-based format | Scientific Literature | |
11. | ALA3285599 | Functional | Antiarrhythmic activity in Hartley guinea pig atria assessed as change in spontaneous rate at 73.2 uM/l after 5 mins | Cavia porcellus | 1 | ALA3272033 | tissue-based format | Scientific Literature | |
12. | ALA3285600 | Functional | Antiarrhythmic activity in Hartley guinea pig atria assessed as change in spontaneous rate at 36.6 uM/l after 5 mins | Cavia porcellus | 1 | ALA3272033 | tissue-based format | Scientific Literature | |
13. | ALA3285874 | Functional | Antiarrhythmic activity in Hartley guinea pig atria assessed as reversible decrease in maximum driving rate compound treated for 5 mins measured up to 2 hrs post washout | Cavia porcellus | 3 | ALA3272033 | tissue-based format | Scientific Literature | |
14. | ALA3284502 | Toxicity | Toxicity in human assessed as numbness at 5 x 10' -5 M administered topically to buccal cavity measured up to 15 to 20 mins | Homo sapiens | 5 | ALA3272033 | organism-based format | Scientific Literature |
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