Antitumor activity against mouse L1210 cells allografted in BDF1 mouse assessed as mean survival time at 0.0125 mg/kg/injection, ip administered daily for 9 days (Rvb = 9.6 days)
Antitumor activity against mouse L1210 cells allografted in BDF1 mouse assessed as mean survival time at 0.15 mg/kg/injection, ip administered intermittently on days 1, 5 and 9 (Rvb = 9.6 days)
Antitumor activity against mouse L1210 cells allografted in BDF1 mouse assessed as mean survival time at 0.2 mg/kg/injection, ip administered as single dose (Rvb = 9.6 days)
Antitumor activity against mouse L1210 cells allografted in BDF1 mouse assessed as increase in life span at 0.0125 mg/kg/injection, ip administered daily for 9 days
Antitumor activity against mouse L1210 cells allografted in BDF1 mouse assessed as increase in lifespan at 0.15 mg/kg/injection, ip administered intermittently on days 1, 5 and 9
Antitumor activity against mouse L1210 cells allografted in BDF1 mouse assessed as increase in life span at 0.2 mg/kg/injection, ip administered as single dose
Antitumor activity against mouse P388 cells allografted in BDF1 mouse assessed as mean survival time at 0.1 mg/kg/injection, ip administered daily for 9 days (Rvb = 10.5 days)
Antitumor activity against mouse P388 cells allografted in BDF1 mouse assessed as mean survival time at 0.15 mg/kg/injection, ip administered intermittently on days 1, 5 and 9 (Rvb = 10.5 days)
Antitumor activity against mouse P388 cells allografted in BDF1 mouse assessed as mean survival time at 0.2 mg/kg/injection, ip administered as single dose (Rvb = 10.5 days)
Antitumor activity against mouse P388 cells allografted in BDF1 mouse assessed as increase in life span at 0.1 mg/kg/injection, ip administered daily for 9 days measured on day 60
Antitumor activity against mouse P388 cells allografted in BDF1 mouse assessed as increase in life span at 0.15 mg/kg/injection, ip administered intermittently on days 1, 5 and 9 measured on day 60
Antitumor activity against mouse P388 cells allografted in BDF1 mouse assessed as increase in life span at 0.2 mg/kg/injection, ip administered as single dose measured on day 60
Antitumor activity against mouse B16 cells allografted in BDF1 mouse assessed as mean survival time at 0.05 mg/kg/injection, ip administered daily for 9 days (Rvb = 28 days)
Antitumor activity against mouse B16 cells allografted in BDF1 mouse assessed as mean survival time at 0.075 mg/kg/injection, ip administered intermittently on days 1, 5 and 9 (Rvb = 28 days)