Antitumor activity against rat Walker 256 cells intramuscularly allografted in rat assessed as survival rate at 0.125 mg/kg, qd administered for 5 days
Antitumor activity against rat Walker 256 cells intramuscularly allografted in rat assessed as survival rate at 0.062 mg/kg, qd administered for 5 days
Antitumor activity against rat Walker 256 cells intramuscularly allografted in rat assessed as survival rate at 0.031 mg/kg, qd administered for 5 days
Antitumor activity against cytoxan-resistant rat Walker 256 cells intramuscularly allografted in rat assessed as survival rate at 1 mg/kg, qd administered for 5 days
Antitumor activity against cytoxan-resistant rat Walker 256 cells intramuscularly allografted in rat assessed as survival rate at 0.5 mg/kg, qd administered for 5 days
Antitumor activity against cytoxan-resistant rat Walker 256 cells intramuscularly allografted in rat assessed as survival rate at 0.25 mg/kg, qd administered for 5 days
Antitumor activity against cytoxan-resistant rat Walker 256 cells intramuscularly allografted in rat assessed as survival rate at 0.12 mg/kg, qd administered for 5 days
Toxicity in rat allografted with cytoxan-resistant rat Walker 256 cells intramuscularly assessed as change in body weight at 2 mg/kg, qd administered for 5 days
Toxicity in rat allografted with cytoxan-resistant rat Walker 256 cells intramuscularly assessed as change in body weight at 1 mg/kg, qd administered for 5 days
Toxicity in rat allografted with cytoxan-resistant rat Walker 256 cells intramuscularly assessed as change in body weight at 0.5 mg/kg, qd administered for 5 days
Toxicity in rat allografted with cytoxan-resistant rat Walker 256 cells intramuscularly assessed as change in body weight at 0.25 mg/kg, qd administered for 5 days