Antitumor activity against rat Walker 256 cells intramuscularly allografted in rat assessed as tumor growth inhibition at 6.25 mg/kg, qd administered for 5 days relative to control
Antitumor activity against rat Walker 256 cells intramuscularly allografted in rat assessed as tumor growth inhibition at 3.12 mg/kg, qd administered for 5 days relative to control
Antitumor activity against rat Walker 256 cells intramuscularly allografted in rat assessed as tumor growth inhibition at 1.56 mg/kg, qd administered for 5 days relative to control
Antitumor activity against rat Walker 256 cells intramuscularly allografted in rat assessed as tumor growth inhibition at 0.78 mg/kg, qd administered for 5 days relative to control
In vivo antitumor activity against mouse L1210 cells in prognostic scoring system assessed as tumor growth inhibition at 5 mg/kg, qd administered for 9 days relative to control
In vivo antitumor activity against mouse L1210 cells in prognostic scoring system assessed as tumor growth inhibition at 3 mg/kg, qd administered for 9 days relative to control
In vivo antitumor activity against mouse L1210 cells in prognostic scoring system assessed as tumor growth inhibition at 1.8 mg/kg, qd administered for 9 days relative to control
In vivo antitumor activity against mouse L1210 cells in prognostic scoring system assessed as tumor growth inhibition at 1 mg/kg, qd administered for 9 days relative to control