# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3282767 | B | Activity at Sprague-Dawley rat pyruvate kinase M assessed as initial enzyme reaction velocity at 0.21 mM by spectrophotometric analysis relative to ADP | Rattus norvegicus | 5 | ALA3272298 | single protein format | Scientific Literature | |
2. | ALA3282768 | B | Activity at Sprague-Dawley rat pyruvate kinase K assessed as initial enzyme reaction velocity at 0.21 mM by spectrophotometric analysis relative to ADP | Rattus norvegicus | 5 | ALA3272298 | assay format | Scientific Literature | |
3. | ALA3282769 | B | Activity at Sprague-Dawley rat pyruvate kinase L assessed as initial enzyme reaction velocity at 0.21 mM by spectrophotometric analysis relative to ADP | Rattus norvegicus | 5 | ALA3272298 | single protein format | Scientific Literature | |
4. | ALA3282771 | B | Inactivation of Sprague-Dawley rat pyruvate kinase L using PEP as substrate at 5 mM at pH 7 after 8 hrs by spectrophotometric analysis | Rattus norvegicus | 9 | ALA3272298 | single protein format | Scientific Literature | |
5. | ALA3282772 | B | Inactivation of Sprague-Dawley rat pyruvate kinase K using PEP as substrate at 5 mM at pH 7 after 8 hrs by spectrophotometric analysis | Rattus norvegicus | 7 | ALA3272298 | assay format | Scientific Literature | |
6. | ALA3282773 | B | Inactivation of Sprague-Dawley rat pyruvate kinase M using PEP as substrate at 5 mM at pH 7 after 24 hrs by spectrophotometric analysis | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
7. | ALA3282774 | B | Inactivation of Sprague-Dawley rat pyruvate kinase L using PEP as substrate at 5 mM at pH 7 after 8 hrs by spectrophotometric analysis in presence of 5 mM ADP | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
8. | ALA3282776 | B | Half life for inactivation of Sprague-Dawley rat pyruvate kinase L using PEP as substrate by spectrophotometric analysis | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
9. | ALA3282777 | B | Binding affinity to Sprague-Dawley rat pyruvate kinase L assessed as apprent enzyme-inhibitor dissociation constant using PEP as substrate by spectrophotometric analysis | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
10. | ALA3285645 | B | Inactivation of Sprague-Dawley rat pyruvate kinase M using PEP as substrate at 7 mM pretreated at 22 degC for 2 hrs with pyruvate kinase L measured for 3.5 hrs by spectrophotometric analysis | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
11. | ALA3285646 | B | Inactivation of Sprague-Dawley rat pyruvate kinase L using PEP as substrate at 7 mM pretreated with pyruvate kinase M measured for 4 hrs by spectrophotometric analysis | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
12. | ALA3285647 | B | Inactivation of Sprague-Dawley rat pyruvate kinase K using PEP as substrate at 7 mM pretreated with pyruvate kinase L by spectrophotometric analysis | Rattus norvegicus | 1 | ALA3272298 | assay format | Scientific Literature | |
13. | ALA3285648 | B | Inactivation of Sprague-Dawley rat pyruvate kinase L using PEP as substrate at 7 mM pretreated with pyruvate kinase K by spectrophotometric analysis | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
14. | ALA3285649 | P | Retardation factor of the compound using 1-butanol-acetic acid-water as solvent system by paper chromatography | 7 | ALA3272298 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA3285650 | A | Drug metabolism assessed as Sprague-Dawley rat pyruvate kinase M-mediated drug conversion | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
16. | ALA3285651 | A | Drug metabolism assessed as Sprague-Dawley rat pyruvate kinase L-mediated drug conversion | Rattus norvegicus | 1 | ALA3272298 | single protein format | Scientific Literature | |
17. | ALA3285652 | A | Drug metabolism assessed as Sprague-Dawley rat pyruvate kinase K-mediated drug conversion | Rattus norvegicus | 1 | ALA3272298 | assay format | Scientific Literature |