| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3295291 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of hsp25 promoter activity after 12 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 2. | ALA3295292 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of hsp70 promoter activity after 12 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 3. | ALA3295293 | B | Inhibition of HSP1 activity in mouse MEF assessed as reduction of hsp25 promoter activity at 5 to 100 uM after 12 hrs by luciferase reporter gene assay | Mus musculus | 1 | ALA3286220 | single protein format | Scientific Literature | |
| 4. | ALA3295294 | B | Inhibition of HSP1 activity in mouse MEF assessed as reduction of hsp70 promoter activity at 5 to 100 uM after 12 hrs by luciferase reporter gene assay | Mus musculus | 1 | ALA3286220 | single protein format | Scientific Literature | |
| 5. | ALA3295295 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP27 mRNA expression at 1 to 20 uM after 12 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 6. | ALA3295296 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP70 mRNA expression at 1 to 20 uM after 12 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 7. | ALA3295297 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP1 mRNA expression at 1 to 20 uM after 12 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 8. | ALA3295298 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP27 mRNA expression at 20 uM up to 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 9. | ALA3295299 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP70 mRNA expression at 20 uM up to 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 10. | ALA3295300 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP1 mRNA expression at 20 uM up to 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 11. | ALA3295301 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP25 protein expression after 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 12. | ALA3295302 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP70 protein expression after 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 13. | ALA3295555 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP1 protein expression after 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 14. | ALA3295556 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP25 protein expression at 20 uM by Western blot analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 15. | ALA3295557 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP70 protein expression at 20 uM by Western blot analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 16. | ALA3295558 | B | Inhibition of HSP1 activity in human NCI-H460 cells assessed as reduction of HSP1 protein expression at 20 uM by Western blot analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 17. | ALA3295559 | B | Reduction of HSP1 stability in human NCI-H460 cells assessed as protein degradation at 10 uM up to 9 hrs by Western blot analysis in presence of cyclohexamide | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 18. | ALA3295561 | B | Induction of HSP1 dephosphorylation at S230, S303/307, and S326 in human NCI-H460 cells after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 19. | ALA3295562 | B | Reduction of HSP1 phosphorylated at S326E mutant stability in human NCI-H460 cells up to 7.5 hrs by Western blot analysis in presence of cyclohexamide | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature | |
| 20. | ALA3295563 | B | Reduction of HSP1 dephosphorylated at S326A mutant stability in human NCI-H460 cells up to 7.5 hrs by Western blot analysis in presence of cyclohexamide | Homo sapiens | 1 | ALA3286220 | cell-based format | Scientific Literature |
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