| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3295460 | F | Antitumor activity against human MDA-MB-435 cells xenografted into flank of athymic BALBc/J mouse assessed as decrease in tumor vascular density at 25 mg/kg twice weekly by CD31/PECAM-1 immunohistochemical staining | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA3295462 | B | Inhibition of bovine brain tubulin assembly preincubated for 15 mins followed by GTP addition measured for 20 mins by spectrophotometry | Bos taurus | 6 | assay format | Scientific Literature | ||
| 3. | ALA3295463 | B | Inhibition of VEGFR2 in human U251 cells by phosphotyrosine ELISA | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA3295464 | F | Growth inhibition of wild type human HeLa cells after 96 hrs incubation by sulforhodamine B technique | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA3295465 | F | Growth inhibition of human HeLa cells overexpressing beta-3 after 96 hrs incubation by sulforhodamine B technique | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA3295466 | F | Growth inhibition of human OVCAR8 cells after 96 hrs incubation by sulforhodamine B technique | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA3295467 | F | Growth inhibition of human NCI/ADR-RES cells overexpressing P-gp after 96 hrs incubation by sulforhodamine B technique | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA3295468 | F | Antiangiogenic activity in chicken chorioallantoic membrane assessed as inhibition of VEGF/bFGF-induced angiogenesis treated 8 hrs after VEGF/bFGF addition measured after 40 hrs by microscopy | Gallus gallus | 2 | cell membrane format | Scientific Literature | ||
| 9. | ALA3295469 | F | Growth inhibition of human NCI60 cells after 96 hrs incubation by sulforhodamine B technique | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3295470 | F | Ratio of IC50 for human OVCAR8 cells to IC50 for human NCI/ADR-RES cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3295471 | B | Disruption of microtubule organization in human MDA-MB-435 cells at IC50 concentration after 2 hrs by immunofluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3295472 | F | Cell cycle arrest in human MDA-MB-435 cells assessed as increase in accumulation at G2/M phase at IC50 concentration after 2 hrs by propidium iodide staining-based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3295473 | F | Induction of apoptosis in human MDA-MB-435 cells assessed as PARP cleavage at IC50 concentration after 48 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3295474 | F | Induction of apoptosis in human MDA-MB-435 cells assessed as caspase 3 cleavage at IC50 concentration after 48 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3295475 | B | Displacement of [3H]-vinblastine from tubulin (unknown origin) relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 16. | ALA3295476 | B | Displacement of [3H]-colchicine from tubulin (unknown origin) at 50 uM relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 17. | ALA3295477 | F | Antitumor activity against human MDA-MB-435 cells xenografted into flank of athymic BALBc/J mouse assessed as decrease in tumor growth at 25 mg/kg twice weekly measured up to 34 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3295481 | T | Toxicity in athymic BALBc/J mouse xenografted with human MDA-MB-435 cells assessed as body weight at 25 mg/kg twice weekly | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3295734 | F | Antitumor activity against human U251 cells xenografted into athymic NCr mouse assessed as decrease in tumor growth at 25 mg/kg twice weekly measured up to 34 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3295737 | T | Toxicity in athymic NCr mouse xenografted with human U251 cells at 25 mg/kg twice weekly measured up to 34 days | Mus musculus | 1 | organism-based format | Scientific Literature |
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