| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3296531 | B | Displacement of [125I]SS14 from human SST3 expressed in CHO membrane after 60 to 90 mins by scintillation counting | Homo sapiens | 43 | cell membrane format | Scientific Literature | ||
| 2. | ALA3296533 | F | Antagonist activity at human SST3 expressed in CHO-K1 cells assessed as inhibition of SRIF-14-induced foreskin-stimulated cAMP accumulation at 2 uM after 45 mins by TR-FRET assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA3296534 | F | Agonist activity at human SST3 expressed in CHO-K1 cells assessed as foreskin-stimulated cAMP accumulation after 45 mins by TR-FRET assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 4. | ALA3296535 | F | Agonist activity at human SST3 expressed in CHO-K1 cells assessed as activation of foreskin-stimulated cAMP accumulation at 2 uM after 45 mins by TR-FRET assay | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 5. | ALA3296536 | B | Displacement of [125I]SS14 from human SST1 expressed in CHO membrane after 60 to 90 mins by scintillation counting | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 6. | ALA3296537 | B | Displacement of [125I]SS14 from human SST2 expressed in CHO membrane after 60 to 90 mins by scintillation counting | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 7. | ALA3296538 | B | Displacement of [125I]SS14 from human SST4 expressed in CHO membrane after 60 to 90 mins by scintillation counting | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 8. | ALA3296539 | B | Displacement of [125I]SS28 from human SST5 expressed in CHO membrane after 60 to 90 mins by scintillation counting | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 9. | ALA3296540 | B | Binding affinity to rhesus monkey SST3 by competition binding assay | Macaca mulatta | 1 | assay format | Scientific Literature | ||
| 10. | ALA3296541 | B | Binding affinity to dog SST3 by competition binding assay | Canis lupus familiaris | 1 | assay format | Scientific Literature | ||
| 11. | ALA3296542 | B | Selectivity ratio of Ki for human SST1 expressed in CHO membrane to Ki for human SST3 expressed in CHO membrane | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 12. | ALA3296543 | B | Selectivity ratio of Ki for human SST2 expressed in CHO membrane to Ki for human SST3 expressed in CHO membrane | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 13. | ALA3296544 | B | Selectivity ratio of Ki for human SST4 expressed in CHO membrane to Ki for human SST3 expressed in CHO membrane | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 14. | ALA3296545 | B | Selectivity ratio of Ki for human SST5 expressed in CHO membrane to Ki for human SST3 expressed in CHO membrane | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 15. | ALA3296549 | F | Increase in glucose excursion in C57BL/6 mouse at 10 mg/kg, po administered 30 mins prior to glucose loading by oral glucose tolerance test relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA3296550 | A | Plasma concentration in C57BL/6 mouse at 10 mg/kg, po after 2.5 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3296552 | B | Agonist activity at dog SST3 expressed in CHO-K1 cells assessed as foreskin-stimulated cAMP accumulation after 45 mins by TR-FRET assay | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3296553 | B | Agonist activity at dog SST3 expressed in CHO-K1 cells assessed as foreskin-stimulated cAMP accumulation at 2 uM after 45 mins by TR-FRET assay | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3296554 | F | Agonist activity at mouse SST3 expressed in CHO-K1 cells assessed as foreskin-stimulated cAMP accumulation after 45 mins by TR-FRET assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3296555 | F | Agonist activity at mouse SST3 expressed in CHO-K1 cells assessed as foreskin-stimulated cAMP accumulation at 2 uM after 45 mins by TR-FRET assay | Mus musculus | 1 | cell-based format | Scientific Literature |
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