#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3293516	B	Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay	Rattus norvegicus	65	ALA3286233	cell-based format	Scientific Literature
2.	ALA3293517	B	Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	65	ALA3286233	cell-based format	Scientific Literature
3.	ALA3293518	B	Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay	Rattus norvegicus	65	ALA3286233	cell-based format	Scientific Literature
4.	ALA3293519	B	Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	65	ALA3286233	cell-based format	Scientific Literature
5.	ALA3293520	P	Apparent permeability of the compound at 100 uM by PAMPA		28	ALA3286233	small-molecule physicochemical format	Scientific Literature
6.	ALA3293521	A	Metabolic stability in rat plasma assessed as compound remaining at 100 uM after 60 mins by LC-MS analysis	Rattus norvegicus	28	ALA3286233	cell-free format	Scientific Literature
7.	ALA3293522	A	Metabolic stability in rat liver microsomes assessed as compound remaining at 4 uM incubated for 5 mins prior to NADPH addition measured after 60 mins by LC-MS analysis	Rattus norvegicus	28	ALA3286233	assay format	Scientific Literature
8.	ALA3293523	B	Modulation of rat mGlu1 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	6	ALA3286233	cell-based format	Scientific Literature
9.	ALA3293525	B	Ago-Positive allosteric modulator activity at rat mGlu2 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	7	ALA3286233	cell-based format	Scientific Literature
10.	ALA3293526	B	Positive allosteric modulation of rat mGlu3 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	5	ALA3286233	cell-based format	Scientific Literature
11.	ALA3293528	B	Modulation of rat mGlu4 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	6	ALA3286233	cell-based format	Scientific Literature
12.	ALA3293765	B	Modulation of rat mGlu5 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	7	ALA3286233	cell-based format	Scientific Literature
13.	ALA3293766	B	Modulation of rat mGlu6 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	6	ALA3286233	cell-based format	Scientific Literature
14.	ALA3295731	B	Modulation of rat mGlu7 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	7	ALA3286233	cell-based format	Scientific Literature
15.	ALA3295732	B	Modulation of rat mGlu8 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate	Rattus norvegicus	7	ALA3286233	cell-based format	Scientific Literature
16.	ALA3291858	A	Cmax in rat at 20 mg/kg, po	Rattus norvegicus	4	ALA3286233	organism-based format	Scientific Literature
17.	ALA3291859	A	Tmax in rat at 20 mg/kg, po	Rattus norvegicus	4	ALA3286233	organism-based format	Scientific Literature
18.	ALA3291860	A	AUC (0 to t) in rat at 20 mg/kg, po	Rattus norvegicus	4	ALA3286233	organism-based format	Scientific Literature
19.	ALA3291861	A	Terminal half life in rat at 20 mg/kg, po	Rattus norvegicus	4	ALA3286233	organism-based format	Scientific Literature
20.	ALA3291862	A	Oral bioavailability in rat at 20 mg/kg	Rattus norvegicus	4	ALA3286233	organism-based format	Scientific Literature