# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3293516 | B | Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay | Rattus norvegicus | 65 | ALA3286233 | cell-based format | Scientific Literature | |
2. | ALA3293517 | B | Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 65 | ALA3286233 | cell-based format | Scientific Literature | |
3. | ALA3293518 | B | Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay | Rattus norvegicus | 65 | ALA3286233 | cell-based format | Scientific Literature | |
4. | ALA3293519 | B | Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 65 | ALA3286233 | cell-based format | Scientific Literature | |
5. | ALA3293524 | B | Antagonist activity at rat mGlu1 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 1 | ALA3286233 | cell-based format | Scientific Literature | |
6. | ALA3293525 | B | Ago-Positive allosteric modulator activity at rat mGlu2 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 7 | ALA3286233 | cell-based format | Scientific Literature | |
7. | ALA3293526 | B | Positive allosteric modulation of rat mGlu3 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 5 | ALA3286233 | cell-based format | Scientific Literature | |
8. | ALA3293529 | B | Antagonist activity at rat mGlu4 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 1 | ALA3286233 | cell-based format | Scientific Literature | |
9. | ALA3293765 | B | Modulation of rat mGlu5 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 7 | ALA3286233 | cell-based format | Scientific Literature | |
10. | ALA3293766 | B | Modulation of rat mGlu6 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 6 | ALA3286233 | cell-based format | Scientific Literature | |
11. | ALA3295731 | B | Modulation of rat mGlu7 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 7 | ALA3286233 | cell-based format | Scientific Literature | |
12. | ALA3295732 | B | Modulation of rat mGlu8 receptor expressed in HEK293 cells at 10 uM incubated for 2.5 mins prior to glutamate addition measured after 2.5 mins by GIRK assay relative to glutamate | Rattus norvegicus | 7 | ALA3286233 | cell-based format | Scientific Literature | |
13. | ALA3294092 | B | Antagonist activity at rat mGlu1 receptor expressed in HEK293 cells | Rattus norvegicus | 1 | ALA3286233 | cell-based format | Scientific Literature | |
14. | ALA3294093 | B | Antagonist activity at rat mGlu4 receptor expressed in HEK293 cells | Rattus norvegicus | 1 | ALA3286233 | cell-based format | Scientific Literature |