| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3292514 | Binding | Inhibition of human ERG | Homo sapiens | 3 | ALA3286180 | single protein format | Scientific Literature | |
| 2. | ALA3292515 | ADME | Time dependent inhibition of CYP (unknown origin) at 50 uM | Homo sapiens | 1 | ALA3286180 | assay format | Scientific Literature | |
| 3. | ALA3292526 | Binding | Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysis | Homo sapiens | 47 | ALA3286180 | single protein format | Scientific Literature | |
| 4. | ALA3292527 | Functional | Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha production after 20 hrs by fluorescence linked immunosorbant assay | Homo sapiens | 16 | ALA3286180 | cell-based format | Scientific Literature | |
| 5. | ALA3292528 | Functional | Antiinflammatory activity in human whole blood assessed as inhibition of LPS-induced TNFalpha production after 20 hrs by ELISA | Homo sapiens | 5 | ALA3286180 | tissue-based format | Scientific Literature | |
| 6. | ALA3292529 | Functional | Antiinflammatory activity in rat whole blood assessed as inhibition of LPS-induced TNFalpha production after 20 hrs by ELISA | Rattus norvegicus | 5 | ALA3286180 | tissue-based format | Scientific Literature | |
| 7. | ALA3292530 | ADME | Fraction unbound in human plasma | Homo sapiens | 16 | ALA3286180 | cell-free format | Scientific Literature | |
| 8. | ALA3292531 | ADME | Fraction unbound in rat plasma | Rattus norvegicus | 5 | ALA3286180 | cell-free format | Scientific Literature | |
| 9. | ALA3292532 | Physicochemical | Aqueous solubility of the compound at pH 7.4 | 16 | ALA3286180 | small-molecule physicochemical format | Scientific Literature | ||
| 10. | ALA3292533 | Physicochemical | Lipophilicity, log D of the compound | 16 | ALA3286180 | small-molecule physicochemical format | Scientific Literature | ||
| 11. | ALA3292534 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 5 | ALA3286180 | assay format | Scientific Literature | |
| 12. | ALA3292535 | ADME | Intrinsic clearance in rat hepatocytes measured per 10'6 cells | Rattus norvegicus | 5 | ALA3286180 | cell-based format | Scientific Literature | |
| 13. | ALA3292536 | ADME | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 10 | ALA3286180 | organism-based format | Scientific Literature | |
| 14. | ALA3292537 | ADME | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 10 | ALA3286180 | organism-based format | Scientific Literature | |
| 15. | ALA3292538 | ADME | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 10 | ALA3286180 | organism-based format | Scientific Literature | |
| 16. | ALA3292539 | ADME | Half life in rat at 1 mg/kg, it | Rattus norvegicus | 5 | ALA3286180 | organism-based format | Scientific Literature | |
| 17. | ALA3292789 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 6 | ALA3286180 | single protein format | Scientific Literature | |
| 18. | ALA3292790 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 6 | ALA3286180 | single protein format | Scientific Literature | |
| 19. | ALA3292791 | Functional | Antiinflammatory activity in Sprague-Dawley rat assessed as inhibition of LPS-induced bronchoalveolar lavage neutrophils at 0.01 mg/ml, inhalation administered as nebulized suspension | Rattus norvegicus | 4 | ALA3286180 | organism-based format | Scientific Literature | |
| 20. | ALA3292792 | Functional | Antiinflammatory activity in Sprague-Dawley rat assessed as inhibition of LPS-induced bronchoalveolar lavage neutrophils measured as LPS duration at 0.01 mg/ml, inhalation administered as nebulized suspension | Rattus norvegicus | 1 | ALA3286180 | organism-based format | Scientific Literature |
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