| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3295496 | B | Inhibition of SIRT6 (unknown origin) at 200 uM by fluorescence-based assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 2. | ALA3295497 | B | Inhibition of SIRT6 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA3295498 | B | Inhibition of SIRT1 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA3295499 | B | Inhibition of SIRT2 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA3295500 | B | Selectivity ratio of IC50 for SIRT1 (unknown origin) to IC50 for SIRT6 (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA3295501 | B | Selectivity ratio of IC50 for SIRT2 (unknown origin) to IC50 for SIRT6 (unknown origin) | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 7. | ALA3295502 | B | Inhibition of SIRT6 in human BxPC3 cells assessed as increase in H3K9 acetylation at 100 uM after 18 hrs by immunoblot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3295503 | B | Inhibition of SIRT6 in human BxPC3 cells assessed as increase in H3K9 acetylation at 100 uM after >18 hrs by immunoblot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3295504 | F | Increase in [14C]-2-deoxy-D-glucose uptake in human BxPC3 cells at 200 uM after 18 hrs by scintillation counting analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3295505 | F | Increase in [14C]-2-deoxy-D-glucose uptake in rat L6 cells at 200 uM after 18 hrs by scintillation counting analysis relative to control | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3295506 | F | Increase in GLUT1 expression in human BxPC3 cells at 12.5 to 200 uM after 24 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3295508 | F | Increase in GLUT1 expression in human BxPC3 cell surface at 100 uM after 24 hrs by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3295509 | F | Inhibition of PMA-induced TNF-alpha secretion in human BxPC3 cells at 100 uM incubated for overnight prior to stimulation of PMA for 24 hrs by ELISA | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA3625951 | B | Inhibition of SIRT6 in human BxPC-3 cells assessed as increase in H3K9 acetylation by immunoblotting assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA3625953 | B | Inhibition of human SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by fluorescence assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 16. | ALA3625954 | B | Inhibition of human recombinant SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by luminescence assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 17. | ALA3625955 | B | Inhibition of human SIRT1 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 18. | ALA3625956 | B | Inhibition of human SIRT2 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 19. | ALA3625957 | B | Selectivity ratio of IC50 for human SIRT1 to IC50 for human SIRT6 | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 20. | ALA3625958 | B | Selectivity ratio of IC50 for human SIRT2 to IC50 for human SIRT6 | Homo sapiens | 4 | assay format | Scientific Literature |
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