# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA679291 | B | Selectivity index which is the ratio of the Ki or IC50 values of recombinant bovine Endothelial nitric oxide synthase and bovine brain nNOS (Neuronal nitric oxide synthase) | 18 | assay format | Scientific Literature | |||
2. | ALA679292 | B | Selectivity index which is the ratio of the Ki or IC50 values of recombinant bovine eNOS (Endothelial nitric oxide synthase) / recombinant murine iNOS (Inducible nitric oxide synthase) | 18 | assay format | Scientific Literature | |||
3. | ALA738697 | F | Inhibitory effect of compound on the accumulation of NO2 in the culture media of N9 cells in response to LPS/IFN-gamma | Mus musculus | 8 | organism-based format | Scientific Literature | ||
4. | ALA738698 | F | Inhibitory effect of compound on the accumulation of NO2 in the culture media of RAW 264.7 cells in response to LPS | Mus musculus | 8 | organism-based format | Scientific Literature | ||
5. | ALA892781 | F | Inhibition of 1ug/ml LPS-stimulated nitirc oxide accumulation in RAW 264 cells after 24 hrs | Mus musculus | 7 | cell-based format | Scientific Literature | ||
6. | ALA946075 | F | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells | Mus musculus | 15 | cell-based format | Scientific Literature | ||
7. | ALA946181 | A | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 3.78 uM by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA946182 | B | Selectivity for iNOS to eNOS | 1 | assay format | Scientific Literature | |||
9. | ALA946183 | B | Selectivity for iNOS to nNOS | 1 | assay format | Scientific Literature | |||
10. | ALA998404 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite accumulation after 24 hrs | Mus musculus | 5 | cell-based format | Scientific Literature | ||
11. | ALA998406 | F | Antiinflammatory activity against mouse N9 cells assessed as inhibition of LPS/IFN-gamma-induced nitrite accumulation after 24 hrs | Mus musculus | 5 | cell-based format | Scientific Literature | ||
12. | ALA1013192 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of nitric oxide production pretreated 1 hr before LPS challenge | Mus musculus | 3 | cell-based format | Scientific Literature | ||
13. | ALA1013196 | F | Antiinflammatory activity in LPS/IFN-gamma-stimulated mouse N9 cells assessed as inhibition of nitric oxide production pretreated 1 hr before LPS/IFNgamma challenge | Mus musculus | 2 | cell-based format | Scientific Literature | ||
14. | ALA1009399 | F | Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as effect on NO production pretreated 1 hr before LPS challenge measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
15. | ALA944278 | B | Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr before LPS challenge by whole cell assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
16. | ALA944279 | B | Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr before LPS challenge by whole cell assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
17. | ALA944280 | B | Selectivity ratio of IC50 for human eNOS to IC50 for human iNOS | Homo sapiens | 7 | assay format | Scientific Literature | ||
18. | ALA950606 | F | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as nitrite accumulation at 10 uM after 20 hrs by fluorimetry relative to control | Mus musculus | 10 | cell-based format | Scientific Literature | ||
19. | ALA942436 | F | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs by fluorimetry | Mus musculus | 10 | cell-based format | Scientific Literature | ||
20. | ALA942438 | F | Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as PGE2 accumulation at 10 uM after 20 hrs by RIA relative to control | Mus musculus | 10 | cell-based format | Scientific Literature |