# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3592389 | Binding | Inhibition of mouse recombinant iNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analysis | Mus musculus | 9 | ALA3588792 | single protein format | Scientific Literature | |
2. | ALA3592390 | Binding | Inhibition of bovine recombinant eNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analysis | Bos taurus | 9 | ALA3588792 | single protein format | Scientific Literature | |
3. | ALA3592391 | Binding | Selectivity ratio of IC50 for bovine recombinant iNOS to IC50 for mouse recombinant iNOS | 5 | ALA3588792 | assay format | Scientific Literature | ||
4. | ALA3592392 | Functional | Reduction of Ach-mediated NO-dependent precontracted Sprague-Dawley rat mesenteric vascular artery vasorelaxation measured at 1 uM/30 mins preincubation | Rattus norvegicus | 1 | ALA3588792 | organism-based format | Scientific Literature | |
5. | ALA3592669 | Functional | Induction of NA-induced LPS-treated Sprague-Dawley rat mesenteric vascular artery vasoconstriction effect measured at 1 uM/30 mins preincubation relative to basal level | Rattus norvegicus | 1 | ALA3588792 | organism-based format | Scientific Literature | |
6. | ALA679291 | Binding | Selectivity index which is the ratio of the Ki or IC50 values of recombinant bovine Endothelial nitric oxide synthase and bovine brain nNOS (Neuronal nitric oxide synthase) | 18 | ALA1132345 | assay format | Scientific Literature | ||
7. | ALA679292 | Binding | Selectivity index which is the ratio of the Ki or IC50 values of recombinant bovine eNOS (Endothelial nitric oxide synthase) / recombinant murine iNOS (Inducible nitric oxide synthase) | 18 | ALA1132345 | assay format | Scientific Literature | ||
8. | ALA892781 | Functional | Inhibition of 1ug/ml LPS-stimulated nitirc oxide accumulation in RAW 264 cells after 24 hrs | Mus musculus | 7 | ALA1147846 | cell-based format | Scientific Literature | |
9. | ALA1072603 | Functional | Inhibition of LPS-induced nitric oxide accumulation in mouse RAW264.7 cells | Mus musculus | 8 | ALA1152565 | cell-based format | Scientific Literature | |
10. | ALA1072605 | Functional | Antioxidant activity assessed as nitric oxide scavenging activity in SNP solution at 10 uM in presence of light after 60 mins | 4 | ALA1152565 | assay format | Scientific Literature | ||
11. | ALA1175354 | Functional | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite production at 50 uM treated 30 mins before LPS challenge measured after 24 hrs by Griess method | Mus musculus | 1 | ALA1177893 | cell-based format | Scientific Literature | |
12. | ALA1273065 | Binding | Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin | Mus musculus | 11 | ALA1268984 | single protein format | Scientific Literature | |
13. | ALA1273066 | Binding | Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin | Rattus norvegicus | 11 | ALA1268984 | assay format | Scientific Literature | |
14. | ALA1273067 | Binding | Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin | Bos taurus | 11 | ALA1268984 | single protein format | Scientific Literature | |
15. | ALA1273068 | Binding | Selectivity ratio, ratio of IC50 for bovine eNOS to IC50 for mouse macrophage iNOS | 11 | ALA1268984 | assay format | Scientific Literature | ||
16. | ALA1273069 | Binding | Selectivity ratio, ratio of IC50 for bovine eNOS to IC50 for rat brain nNOS | 11 | ALA1268984 | assay format | Scientific Literature | ||
17. | ALA1273070 | Binding | Selectivity ratio, ratio of IC50 for mouse macrophage iNOS to IC50 for rat brain nNOS | 11 | ALA1268984 | assay format | Scientific Literature | ||
18. | ALA1741321 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
19. | ALA1741322 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
20. | ALA1741323 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays |