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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3294050 F Agonist activity at human GPR40 expressed in CHO cells by calcium flux assay Homo sapiens 23 ALA3286210 cell-based format Scientific Literature 2. ALA3294051 F Agonist activity at rat GPR40 expressed in CHO cells by calcium flux assay Rattus norvegicus 23 ALA3286210 cell-based format Scientific Literature 3. ALA3294052 P Lipophilicity, log D of the compound at pH 7.4 23 ALA3286210 small-molecule physicochemical format Scientific Literature 4. ALA3294053 B Inhibition of mitochondrial respiratory chain complex 1 (unknown origin) at 100 uM Homo sapiens 12 ALA3286210 assay format Scientific Literature 5. ALA3294055 A Clearance in F344 rat at 2 mg/kg, iv Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 6. ALA3294057 A Volume of distribution at steady state in F344 rat at 2 mg/kg, iv Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 7. ALA3294059 A Half life in F344 rat at 2 mg/kg, iv Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 8. ALA3294061 A Cmax in F344 rat at 3 mg/kg, po Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 9. ALA3294063 A AUC in F344 rat at 3 mg/kg, po Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 10. ALA3294065 A Oral bioavailability in F344 rat at 3 mg/kg Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 11. ALA3294319 F Insulinotropic effect in mouse MIN6 cells in presence of 25 mM glucose Mus musculus 1 ALA3286210 cell-based format Scientific Literature 12. ALA3294320 F Antidiabetic activity in po dosed diabetic Zucker fatty rat model assessed as reduction of blood glucose level administered 30 mins prior to glucose challenge by oral glucose tolerance test Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 13. ALA3294322 F Antidiabetic activity in diabetic Zucker fatty rat model assessed as reduction of blood glucose level at 3 mg/kg, po administered 30 mins prior to glucose challenge by oral glucose tolerance test relative to sitagliptin Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 14. ALA3294323 F Antidiabetic activity in diabetic Zucker fatty rat model assessed as increase in insulin level measured during OGTT at 1 to 10 mg/kg, po administered 30 mins prior to glucose challenge Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 15. ALA3294324 A Cmax in diabetic Zucker fatty rat model measured during OGTT at 1 mg/kg, po administered 30 mins prior to glucose challenge Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 16. ALA3294325 A Cmax in diabetic Zucker fatty rat model measured during OGTT at 3 mg/kg, po administered 30 mins prior to glucose challenge Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 17. ALA3294326 A Cmax in diabetic Zucker fatty rat model measured during OGTT at 10 mg/kg, po administered 30 mins prior to glucose challenge Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 18. ALA3294327 A AUC in diabetic Zucker fatty rat model measured during OGTT at 1 mg/kg, po administered 30 mins prior to glucose challenge Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 19. ALA3294328 A AUC in diabetic Zucker fatty rat model measured during OGTT at 3 mg/kg, po administered 30 mins prior to glucose challenge Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature 20. ALA3294329 A AUC in diabetic Zucker fatty rat model measured during OGTT at 10 mg/kg, po administered 30 mins prior to glucose challenge Rattus norvegicus 1 ALA3286210 organism-based format Scientific Literature