| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3295851 | F | Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling by fluorescence plate reader analysis in presence of glutamate at EC76 concentration | Rattus norvegicus | 24 | ALA3286359 | cell-based format | Scientific Literature | |
| 2. | ALA3295852 | F | Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling by fluorescence plate reader analysis in presence of glutamate at EC87 concentration | Rattus norvegicus | 24 | ALA3286359 | cell-based format | Scientific Literature | |
| 3. | ALA3295855 | F | Negative allosteric modulatory activity at rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling by fluorescence plate reader analysis in presence of glutamate at EC76 concentration | Rattus norvegicus | 1 | ALA3286359 | cell-based format | Scientific Literature | |
| 4. | ALA3295856 | F | Negative allosteric modulatory activity at rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling by fluorescence plate reader analysis in presence of glutamate at EC87 concentration | Rattus norvegicus | 1 | ALA3286359 | cell-based format | Scientific Literature | |
| 5. | ALA3295857 | F | Activity at human mGlu1 receptor assessed as shift in dose-response curve for glutamate-induced calcium signaling at 10 uM by fluorescence plate reader analysis | Homo sapiens | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 6. | ALA3295858 | F | Inhibition of rat mGlu2 receptor assessed as decrease in glutamate-induced calcium signaling at 10 uM by fluorescence plate reader analysis | Rattus norvegicus | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 7. | ALA3295859 | F | Inhibition of rat mGlu3 receptor assessed as decrease in glutamate-induced calcium signaling at 10 uM by fluorescence plate reader analysis | Rattus norvegicus | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 8. | ALA3295860 | F | Activity at rat mGlu5 receptor assessed as glutamate-induced calcium signaling at 10 uM by fluorescence plate reader analysis | Rattus norvegicus | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 9. | ALA3295861 | B | Activity at rat mGlu4 receptor assessed as glutamate-induced GIRK response at 10 uM | Rattus norvegicus | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 10. | ALA3295862 | B | Activity at human mGlu6 receptor assessed as glutamate-induced GIRK response at 10 uM | Homo sapiens | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 11. | ALA3295863 | B | Activity at rat mGlu7 receptor assessed as glutamate-induced GIRK response at 10 uM | Rattus norvegicus | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 12. | ALA3295864 | B | Activity at rat mGlu8 receptor assessed as glutamate-induced GIRK response at 10 uM | Rattus norvegicus | 1 | ALA3286359 | single protein format | Scientific Literature | |
| 13. | ALA3295865 | A | Fraction unbound in human plasma | Homo sapiens | 1 | ALA3286359 | cell-free format | Scientific Literature | |
| 14. | ALA3295866 | A | Fraction unbound in rat plasma | Rattus norvegicus | 1 | ALA3286359 | cell-free format | Scientific Literature |
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