| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3294517 | B | Displacement of [3H]PDBu from recombinant human PKC-alpha after 5 mins by scintillation counting analysis in presence of phosphatidylserine | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 2. | ALA3294518 | B | Displacement of [3H]PDBu from recombinant human PKC-epsilon after 5 mins by scintillation counting analysis in presence of phosphatidylserine | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 3. | ALA3294519 | B | Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis in presence of phosphatidylserine | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 4. | ALA3294520 | B | Selectivity ratio of Ki for recombinant human PKC-alpha to Ki for recombinant human GFP-tagged RasGRP3 | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA3294521 | B | Selectivity ratio of Ki for recombinant human PKC-epsilon to Ki for recombinant human GFP-tagged RasGRP3 | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 6. | ALA3294522 | B | Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphatidylserine | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 7. | ALA3294523 | B | Selectivity ratio of Ki for recombinant human PKC-epsilon to Ki for recombinant RasGRP1 C1 domain (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 8. | ALA3294524 | B | Selectivity ratio of Ki for recombinant human PKC-alpha to Ki for recombinant RasGRP1 C1 domain (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 9. | ALA3294526 | B | Activation of RasGRP3 (unknown origin) overexpressed in HEK293 cells assessed as protein phosphorylation at T133 at 0.1 to 30 uM after 30 mins by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA3294527 | B | Activation of PKC-delta in HEK293 cells assessed as protein phosphorylation at S299 at 0.1 to 30 uM after 30 mins by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA3294528 | B | Activation of PKC-delta in HEK293 cells overexpressing RasGRP3 assessed as protein phosphorylation at S299 at 0.1 to 30 uM after 30 mins by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA3294529 | B | Activation of RasGRP3 (unknown origin) overexpressed in HEK293 cells assessed as ERK1/2 phosphorylation at 0.1 to 30 uM after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 13. | ALA3294530 | B | Activation of RasGRP3 in human Ramos cells assessed as ERK1/2 phosphorylation at 10000 nM after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA3294531 | B | Activation of PKC-delta in human Ramos cells assessed as protein phosphorylation at S299 at 10000 nM after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA3294532 | B | Activation of PKC in human Ramos cells assessed as PKD1 phosphorylation at S744/S748 at 10000 nM after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA3294533 | B | Binding affinity to recombinant human GFP-tagged PKC-alpha expressed in CHOK1 cells assessed as induction of protein translocation from plasma membrane to internal membrane at 10000 nM after 5 to 15 mins by confocal microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA3294536 | B | Binding affinity to recombinant human YFP-tagged PKC-epsilon expressed in human LNCAP cells assessed as induction of protein translocation from plasma membrane to internal membrane at 10000 nM after 2 to 10 mins by confocal microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA3294538 | B | Binding affinity to recombinant human GFP-tagged PKC-delta expressed in human LNCAP cells assessed as induction of protein translocation from plasma membrane to internal membrane at 10000 nM after 2 to 10 mins by confocal microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA3294540 | B | Binding affinity to recombinant human GFP-tagged RasGRP3 expressed in human LNCAP cells assessed as induction of protein translocation from plasma membrane to internal membrane at 10000 nM after 2 to 10 mins by confocal microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA3294542 | B | Binding affinity to DHP-TMA embedded 9:1 DMPC/DMPG giant vesicle at 2.42 to 6.05 uM by fluorescence anisotropy method | 5 | assay format | Scientific Literature |
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