| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3293334 | A | Drug metabolism assessed as human NTPDase-1-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA3293335 | A | Drug metabolism assessed as human NTPDase-2-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA3293336 | A | Drug metabolism assessed as human NTPDase-3-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA3293337 | A | Drug metabolism assessed as human NTPDase-8-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA3293338 | A | Drug metabolism assessed as human NPP1-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA3293339 | A | Drug metabolism assessed as human NPP3-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA3293347 | B | Inhibition of human NPP1 using pNP-TMP as substrate at 100 uM after 20 mins by reversed-phase HPLC analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 8. | ALA3293348 | B | Inhibition of human NPP1 using ATP as substrate at 100 uM after 20 mins by reversed-phase HPLC analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 9. | ALA3293349 | B | Inhibition of NPP1 in human HTB-85 cells using pNP-TMP as substrate at 100 uM after 20 mins by reversed-phase HPLC analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA3293350 | B | Inhibition of human NPP3 using pNP-TMP as substrate at 100 uM after 20 mins by reversed-phase HPLC analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 11. | ALA3293566 | B | Inhibition of human NTPDase-1 using ATP as substrate assessed as inorganic phosphate release at 100 uM after 15 mins relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 12. | ALA3293567 | B | Inhibition of human NTPDase-2 using ATP as substrate assessed as inorganic phosphate release at 100 uM after 15 mins relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 13. | ALA3293568 | B | Inhibition of human NTPDase-3 using ATP as substrate assessed as inorganic phosphate release at 100 uM after 15 mins relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 14. | ALA3293569 | B | Inhibition of human NTPDase-8 using ATP as substrate assessed as inorganic phosphate release at 100 uM after 15 mins relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 15. | ALA3293571 | B | Mixed type inhibition of human NPP1 using pNP-TMP as substrate after 20 mins by Dixon and Cornish-Bowden method | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 16. | ALA3293572 | B | Mixed type inhibition of human NPP1 using pNP-TMP as substrate assessed as dissociation constant for enzyme-inhibitor-substrate complex after 20 mins by Dixon and Cornish-Bowden method | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 17. | ALA3293573 | F | Agonist activity at human P2Y1 receptor expressed in human 1321N1 cells assessed as increase of intracellular calcium level up to 10 uM after 30 mins using fura-2 AM by fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA3293576 | F | Agonist activity at human P2Y11 receptor expressed in human 1321N1 cells assessed as increase of intracellular calcium level after 30 mins using fura-2 AM by fluorescence assay relative to ATP | Homo sapiens | 3 | cell-based format | Scientific Literature |
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