| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3293383 | B | Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA3293384 | B | Agonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA3293388 | B | Antagonist activity at alpha4beta1 integrin in human Jurkat E6.1 cells assessed as inhibition of VCAM1-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3293389 | B | Antagonist activity at alphaLbeta2 integrin in human Jurkat E6.1 cells assessed as inhibition of ICAM1-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3293603 | B | Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3293604 | B | Agonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as increase of cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3291695 | B | Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of fibronectin-mediated cell adhesion at 10 ug/ml after 30 mins by fluorescence assay in presence of neutralizing antibody of beta1 | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3291696 | B | Agonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as increase of fibronectin-mediated cell adhesion at 10 ug/ml after 30 mins by fluorescence assay in presence of neutralizing antibodies of alphav | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3291697 | B | Agonist activity at alpha2bbeta3 integrin in PMA-stimulated human K562 cells assessed as increase of cell adhesion after 30 mins by flow cytometry in presence of tirofiban | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4681195 | B | Inhibition of fibrinogen binding to alpha2bbeta3 isolated from human HEL cells incubated for 1 hr by scintillation-proximity assay based competitive solid-phase binding assay | Homo sapiens | 12 | tissue-based format | Scientific Literature | ||
| 11. | ALA4681196 | B | Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive solid-phase binding assay | Homo sapiens | 12 | tissue-based format | Scientific Literature | ||
| 12. | ALA4681197 | T | Toxicity in human SK-MEL-24 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 13. | ALA4681198 | T | Toxicity in human MCF7 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 14. | ALA4681199 | T | Toxicity in human HT-29 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 15. | ALA4681200 | T | Toxicity in human K562 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 16. | ALA4681201 | T | Toxicity in human HEL cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 17. | ALA4681202 | B | Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 18. | ALA4681206 | B | Agonist activity at alphaVbeta5 in human MCF7 cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 19. | ALA4681208 | B | Agonist activity at alphaVbeta6 in human HT-29 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 20. | ALA4681209 | B | Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 18 | cell-based format | Scientific Literature |
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