# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3293383 | B | Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA3293384 | B | Agonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA3293385 | B | Selectivity ratio of EC50 for alphavbeta3 integrin in human SK-MEL-24 cells to EC50 for alpha5beta1 integrin in human K562 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4323764 | B | Activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as effect on fibronectin-induced cell adhesion pre-incubated for 30 mins | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
5. | ALA4323768 | B | Agonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 30 mins | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA4323770 | B | Activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as effect on VCAM1-induced cell adhesion pre-incubated for 30 mins | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
7. | ALA4681197 | T | Toxicity in human SK-MEL-24 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
8. | ALA4681198 | T | Toxicity in human MCF7 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
9. | ALA4681199 | T | Toxicity in human HT-29 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
10. | ALA4681200 | T | Toxicity in human K562 cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
11. | ALA4681201 | T | Toxicity in human HEL cells assessed as induction of cell necrosis and/or apoptosis incubated for 3 hrs by annexin V-PE and 7-AAD staining based by flow cytometry | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
12. | ALA4681202 | B | Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
13. | ALA4681203 | B | Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
14. | ALA4681206 | B | Agonist activity at alphaVbeta5 in human MCF7 cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
15. | ALA4681207 | B | Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
16. | ALA4681208 | B | Agonist activity at alphaVbeta6 in human HT-29 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
17. | ALA4681209 | B | Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
18. | ALA4681210 | B | Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
19. | ALA4681212 | B | Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and further incubated for 30 mins by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
20. | ALA4681213 | B | Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen and further incubated for 1 hr by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 18 | cell-based format | Scientific Literature |