# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3295678 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in cell growth by measuring DNA level after 7 days by fluorescence analysis | Homo sapiens | 9 | ALA3286188 | cell-based format | Scientific Literature | |
2. | ALA3295679 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in cell growth by measuring DNA level at 10'-6 M after 7 days by fluorescence analysis | Homo sapiens | 6 | ALA3286188 | cell-based format | Scientific Literature | |
3. | ALA3295682 | B | Antagonist activity at ER in human MCF7:WS8 cells assessed as inhibition of estradiol-induced cell growth by measuring DNA level after 7 days treated at highesy drug concentration by fluorescence analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
4. | ALA3295687 | B | Agonist activity at ER in rat GH3 cells assessed as increase in prolactin mRNA level at 10'-13 to 10'-6 M after 48 hrs by RT-PCR analysis relative to estradiol | Rattus norvegicus | 11 | ALA3286188 | cell-based format | Scientific Literature | |
5. | ALA3295689 | B | Antagonist activity at ER in rat GH3 cells assessed as inhibition of estradiol-induced prolactin gene expression at 10'-10 to 10'-6 M after 48 hrs by RT-PCR analysis | Rattus norvegicus | 9 | ALA3286188 | cell-based format | Scientific Literature | |
6. | ALA3295693 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in pS2 gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
7. | ALA3295694 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in GREB1 gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
8. | ALA3295695 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in PgR gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
9. | ALA3291522 | F | Effect on ER-alpha protein level in human MCF7:WS8 cells after 24 hrs by Western blot analysis relative to control | Homo sapiens | 13 | ALA3286188 | cell-based format | Scientific Literature |